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NCT01168739 · ClinicalTrials.gov registry record · NA
Effect of Combined Exercise, Heat, and Quercetin Supplementation on Whole Body Stress Response
A NA study of Heat Acclimation and Thermotolerance, sponsored by University of New Mexi.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
- 1
- Study location
NCT01168739: Completed NA study of Heat Acclimation and Thermotolerance, sponsored by University of New Mexi.
NCT01168739 is a NA study of Heat Acclimation and Thermotolerance that has completed, run by University of New Mexi. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01168739, a NA study of Heat Acclimation and Thermotolerance, has completed, sponsored by University of New Mexi.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether dietary quercetin supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I. To determine if quercetin in combination with repeated bouts of thermally stressful exercise will impact intestinal barrier function. The investigators will examine urinary lactulose excretion, plasma endotoxin,plasma quercetin, inflammatory cytokines (TNF-a \& Il-6), anti-inflammatory cytokines (Il-10), and HSP70 and HSF-1 content of peripheral blood mononuclear cells. Specific Aim II. To determine whether quercetin's suppresses the ability of human subjects to acclimate to exercise/heat stress. The investigators will examine body temperatures, heart rates, physiological strain, sweat and plasma volume responses to standardized heat tolerance tests.
Primary Outcome
Lactulose is a large molecule (disaccharide: 242 kDa) that should not be permeable to the gastrointestinal barrier under normal conditions. Subjects will ingest a test solution containing 10 g lactulose (Quintron Instrument Company, QT02500-10-5, Milwaukee, WI, USA) dissolved in 50 ml of distilled water. This is followed by 8 hour urine collection.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT Quercetin
Study Locations (1)
New Mexico
- UNM General Clinical Research Center - Albuquerque
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2009-09 |
| Est. Completion | 2010-03 |
| Phase | NA |
What the finished NCT01168739 record still lists
NCT01168739 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Heat Acclimation and Thermotolerance appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT01168739 reports a single indexed study location in New Mexico.
Frequently Asked Questions
What is clinical trial NCT01168739 about?
NCT01168739 is a clinical study titled "Effect of Combined Exercise, Heat, and Quercetin Supplementation on Whole Body Stress Response". The purpose of this study is to determine whether dietary quercetin supplementation effects thermotolerance and heat acclimation in human subjects exposed to exercise/heat stress. Specific Aim I. To determine if quercetin in combination with repeated bouts of thermally stressful exercise will impac...
What is the current status of trial NCT01168739?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2009-09. Estimated completion is 2010-03.
What conditions does trial NCT01168739 study?
This clinical trial studies the following conditions: Heat Acclimation and Thermotolerance.
What interventions are being tested in trial NCT01168739?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Quercetin (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01168739?
This trial is sponsored by University of New Mexi, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01168739 being conducted?
This trial has 1 study location across New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01168739's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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