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NCT01167725 · ClinicalTrials.gov registry record · Phase 3
Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer
A Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.
- Terminated
- Registry status
- Phase 3
- Development phase
- 340
- Enrollment target
NCT01167725: Clinical Trial Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.
NCT01167725 is a Phase 3 study that was terminated before completion, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 340 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (56% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01167725, a Phase 3 study, was terminated before completion, sponsored by Alliance for Clinical Trials in Oncology.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 340 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Heating mitomycin C to several degrees above normal body temperature and infusing it into the area around the tumor may kill more tumor cells. Giving mitomycin C after surgery may kill any remaining tumor cells. It is not yet known whether standard therapy is more effective with or without surgery followed by mitomycin C. PURPOSE: This randomized phase III trial is studying standard therapy with or without surgery and mitomycin C in treating patients with advanced limited peritoneal dissemination of colon cancer
Interventions
- DRUG FOLFOX regimen
- BIOLOGICAL cetuximab
- DRUG capecitabine
- BIOLOGICAL bevacizumab
- DRUG FOLFIRI regimen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 340 participants |
| Start Date | 2010-08 |
| Est. Completion | 2012-01 |
| Phase | Phase 3 |
Why NCT01167725 stopped before completion
NCT01167725 is an interventional study that assigns participants to a tested intervention. The registered 340 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (56% lower).
The record links to 0 conditions, and to 5 interventions - of which FOLFOX regimen is the first listed.
NCT01167725 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01167725 about?
NCT01167725 is a clinical study titled "Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer". RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Heating mitomycin C to several degrees above normal body temperature and infusing it into the area around the tumor may kill more tumor cells...
What is the current status of trial NCT01167725?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 340 participants. The study started on 2010-08. Estimated completion is 2012-01.
What interventions are being tested in trial NCT01167725?
The interventions under investigation include: FOLFOX regimen (DRUG), cetuximab (BIOLOGICAL), capecitabine (DRUG), bevacizumab (BIOLOGICAL), FOLFIRI regimen (DRUG).
Who is sponsoring clinical trial NCT01167725?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01167725's enrollment target sits among peer trials
340 1053rd of 2000 higher than 945 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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