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ACTIVE NOT RECRUITING Phase 3

Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

NCT01167712 · View on ClinicalTrials.gov ↗

Study Summary

This phase III clinical trial studies two different dose schedules of paclitaxel to see how well they work in combination with carboplatin with or without bevacizumab in treating patients with stage II, III or IV ovarian epithelial cancer, primary peritoneal cancer, or fallopian tube cancer. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bevacizumab is a type of drug called a monoclonal antibody and blocks tumor growth by stopping the growth of blood vessels that tumors need to grow. It is not yet known whether giving paclitaxel with combination chemotherapy once every three weeks is more effective than giving paclitaxel once a week in treating patients with ovarian, primary peritoneal, or fallopian tube cancer.

Interventions

  • DRUG Carboplatin
  • PROCEDURE Computed Tomography
  • DRUG Paclitaxel
  • PROCEDURE Therapeutic Conventional Surgery
  • BIOLOGICAL Bevacizumab

Study Locations (20)

California

  • Kaiser Permanente-Deer Valley Medical Center — Antioch
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank
  • East Bay Radiation Oncology Center — Castro Valley
  • Valley Medical Oncology Consultants-Castro Valley — Castro Valley
  • John Muir Medical Center-Concord — Concord
  • Bay Area Breast Surgeons Inc — Emeryville
  • Kaiser Permanente-Fremont — Fremont
  • Valley Medical Oncology Consultants-Fremont — Fremont
  • Kaiser Permanente-Fresno — Fresno
  • Marin Cancer Care Inc — Greenbrae

Arizona

  • Saint Joseph's Hospital and Medical Center — Phoenix
  • Mayo Clinic in Arizona — Scottsdale
  • University of Arizona Cancer Center-Orange Grove Campus — Tucson
  • Banner University Medical Center - Tucson — Tucson
  • University of Arizona Cancer Center-North Campus — Tucson

Alabama

  • University of Alabama at Birmingham Cancer Center — Birmingham
  • University of South Alabama Mitchell Cancer Institute — Mobile

Arkansas

  • CHI Saint Vincent Cancer Center Hot Springs — Hot Springs
  • University of Arkansas for Medical Sciences — Little Rock

Alaska

  • Providence Alaska Medical Center — Anchorage

Trial Details

FieldValue
Enrollment Target 692 participants
Start Date 2010-09-27
Est. Completion 2026-07-02
Phase Phase 3

Sponsor

National Cancer Institute (NCI)

2,390 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01167712

The ClinicalTrials.gov registry entry for NCT01167712 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 692 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 2,390 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 10 conditions, with Ovarian Endometrioid Adenocarcinoma appearing as the primary indexed condition, and to 5 interventions — of which Carboplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01167712 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Arizona, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01167712 about?

NCT01167712 is a clinical study titled "Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer". This phase III clinical trial studies two different dose schedules of paclitaxel to see how well they work in combination with carboplatin with or without bevacizumab in treating patients with stage II, III or IV ovarian epithelial cancer, primary peritoneal cancer, or fallopian tube cancer. Drugs u...

What is the current status of trial NCT01167712?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 692 participants. The study started on 2010-09-27. Estimated completion is 2026-07-02.

What conditions does trial NCT01167712 study?

This clinical trial studies the following conditions: Ovarian Endometrioid Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Ovarian Serous Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma, Fallopian Tube Mucinous Adenocarcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01167712?

The interventions under investigation include: Carboplatin (DRUG), Computed Tomography (PROCEDURE), Paclitaxel (DRUG), Therapeutic Conventional Surgery (PROCEDURE), Bevacizumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01167712?

This trial is sponsored by National Cancer Institute (NCI), which has 2,390 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01167712 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial