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NCT01158079 · ClinicalTrials.gov registry record · Phase 1

Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment

A Phase 1 study, sponsored by Alnylam Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
7
Enrollment target

NCT01158079: Completed Phase 1 study, sponsored by Alnylam Pharmaceuticals.

NCT01158079 is a Phase 1 study that has completed, run by Alnylam Pharmaceuticals. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01158079, a Phase 1 study, has completed, sponsored by Alnylam Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
7 participants
Enrollment target

Study Summary

This study provides a mechanism for continued administration of ALN-VSP02 therapy to patients with cancer who completed participation in another ALN-VSP02 clinical study. The primary objective of this study is to collect long term safety data.

Primary Outcome

Patients remain on treatment until disease progression or an adverse event. Adverse events are assessed throughout treatment.

Interventions

  • DRUG ALN-VSP02

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2010-07
Est. Completion 2012-09
Phase Phase 1
Alnylam Pharmaceuticals

49 total trials

What the finished NCT01158079 record still lists

NCT01158079 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).

The record links to 0 conditions, and to 1 intervention - of which ALN-VSP02 is the first listed.

NCT01158079 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01158079 about?

NCT01158079 is a clinical study titled "Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment". This study provides a mechanism for continued administration of ALN-VSP02 therapy to patients with cancer who completed participation in another ALN-VSP02 clinical study. The primary objective of this study is to collect long term safety data.

What is the current status of trial NCT01158079?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2010-07. Estimated completion is 2012-09.

What interventions are being tested in trial NCT01158079?

The interventions under investigation include: ALN-VSP02 (DRUG).

Who is sponsoring clinical trial NCT01158079?

This trial is sponsored by Alnylam Pharmaceuticals, which has 49 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01158079's enrollment target sits among peer trials

7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01158079, the US trial registry maintained by the National Library of Medicine. NCT01158079 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.