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NCT01157533 · ClinicalTrials.gov registry record · NA

Utility of Vancomycin Loading: A Pharmacokinetic Analysis in Critically Ill Patients

A NA study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
NA
Development phase
1
Enrollment target

NCT01157533: Clinical Trial NA study, sponsored by M.D. Anderson Cancer Center.

NCT01157533 is a NA study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01157533, a NA study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
NA
Development phase
1 participants
Enrollment target

Study Summary

The goal of this clinical research study is to learn if giving a larger than normal "loading dose" of the antibiotic vancomycin before starting standard vancomycin dosing can help patients reach and maintain the needed blood-level of the antibiotic during treatment.

Primary Outcome

Peak level (PK blood samples) drawn 4 hours after the completion of loading dose. Sequential trough levels drawn 30 minutes before each standard vancomycin dose for the next 4 doses. PK testing measures the amount of study drug in the body at different time points, with trough testing following 5 doses (1 dose every 8 to 12 hours).

Interventions

  • DRUG Vancomycin

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2010-06
Est. Completion 2012-01
Phase NA
M.D. Anderson Cancer Center

2,692 total trials

Why NCT01157533 stopped before completion

NCT01157533 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 1 intervention - of which Vancomycin is the first listed.

NCT01157533 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01157533 about?

NCT01157533 is a clinical study titled "Utility of Vancomycin Loading: A Pharmacokinetic Analysis in Critically Ill Patients". The goal of this clinical research study is to learn if giving a larger than normal "loading dose" of the antibiotic vancomycin before starting standard vancomycin dosing can help patients reach and maintain the needed blood-level of the antibiotic during treatment.

What is the current status of trial NCT01157533?

This trial is currently terminated. It is a NA study. The enrollment target is 1 participants. The study started on 2010-06. Estimated completion is 2012-01.

What interventions are being tested in trial NCT01157533?

The interventions under investigation include: Vancomycin (DRUG).

Who is sponsoring clinical trial NCT01157533?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01157533's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01157533, the US trial registry maintained by the National Library of Medicine. NCT01157533 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.