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NCT01157429 · ClinicalTrials.gov registry record · Phase 2

D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents

A Phase 2 study, sponsored by Tulane University School of Medicine.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target

NCT01157429: Completed Phase 2 study, sponsored by Tulane University School of Medicine.

NCT01157429 is a Phase 2 study that has completed, run by Tulane University School of Medicine. The registered enrollment target is 24 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01157429, a Phase 2 study, has completed, sponsored by Tulane University School of Medicine.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target

Study Summary

The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18 year-old children.

Primary Outcome

The CPSS is a 17-item standardized, self-administered questionnaires with versions for both youths and caregivers. Items are scored on 0-3 scale. Minimum possible score is 0 and maximum is 51. Only the total score is used; there are no subscales. A higher score indicates greater symptom severity (worse).

Interventions

  • DRUG Placebo pill
  • BEHAVIORAL CBT
  • DRUG D-cycloserine

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2010-06
Est. Completion 2012-06
Phase Phase 2

What the finished NCT01157429 record still lists

NCT01157429 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo pill is the first listed.

NCT01157429 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01157429 about?

NCT01157429 is a clinical study titled "D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents". The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18 year-old children.

What is the current status of trial NCT01157429?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2010-06. Estimated completion is 2012-06.

What interventions are being tested in trial NCT01157429?

The interventions under investigation include: Placebo pill (DRUG), CBT (BEHAVIORAL), D-cycloserine (DRUG).

Who is sponsoring clinical trial NCT01157429?

This trial is sponsored by Tulane University School of Medicine, which has 16 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01157429's enrollment target sits among peer trials

24 1756th of 2000 higher than 217 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01157429, the US trial registry maintained by the National Library of Medicine. NCT01157429 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.