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NCT01153438 · ClinicalTrials.gov registry record
Relationship Between Changes in Gut Hormones After Gastric Bypass and Gastric Banding and Improvements in Diabetes
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 8
- Enrollment target
NCT01153438: Completed study, sponsored by University of Pennsylvania.
NCT01153438 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 8 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01153438 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to see how hormones that control blood sugar change in response to two different weight loss surgeries (gastric bypass and gastric banding). We believe that changes in a hormone called glucagon-like peptide-1 (GLP-1) may account for the greater improvement in blood sugar after certain types of surgeries. GLP-1 makes the pancreas release insulin, a hormone that lowers blood sugar. The study will consist of one screening visit and three study visits in which the glucose response will be measured after drinking a liquid meal: 1) Visit 1 (2-3 weeks before surgery); 2) Visit 2 (after 10% of body weight is lost); and 3) Visit 3 (5-10 days after Visit 2). Hormone levels will be measured during the three study visits. To see if the improvement in blood sugar after surgery is due to changes in GLP-1, we will block its effect on insulin release by giving either salt water or a medication that blocks the activity of GLP-1 during the two visits that take place after surgery (Visits 2 and 3).
Primary Outcome
To compare change in glucose tolerance, independent of weight loss, between obese, diabetic participants who undergo gastric bypass or gastric banding.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2011-04 |
| Est. Completion | 2013-06 |
What the finished NCT01153438 record still lists
NCT01153438 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 8 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01153438 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01153438 about?
NCT01153438 is a clinical study titled "Relationship Between Changes in Gut Hormones After Gastric Bypass and Gastric Banding and Improvements in Diabetes". The purpose of this study is to see how hormones that control blood sugar change in response to two different weight loss surgeries (gastric bypass and gastric banding). We believe that changes in a hormone called glucagon-like peptide-1 (GLP-1) may account for the greater improvement in blood sugar...
What is the current status of trial NCT01153438?
This trial is currently completed. The enrollment target is 8 participants. The study started on 2011-04. Estimated completion is 2013-06.
Who is sponsoring clinical trial NCT01153438?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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