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NCT01150526 · ClinicalTrials.gov registry record · Phase 1

Efficacy of a New Delivery System for Beta-hydroxy-beta-methylbutyrate

A Phase 1 study, sponsored by Metabolic Technologies.

Completed
Registry status
Phase 1
Development phase
41
Enrollment target

NCT01150526 is a Phase 1 study that has completed, run by Metabolic Technologies. The registered enrollment target is 41 participants.

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The verdict

NCT01150526, a Phase 1 study, has completed, sponsored by Metabolic Technologies.

COMPLETED
Registry status
Phase 1
Development phase
41 participants
Enrollment target

Study Summary

The proposed study will test efficacy of HMB in free acid gel to decrease muscle damage, diminish inflammatory response, and improve muscle strength recovery following an acute exercise stress. HMB in a free acid gel or in CaHMB capsule form will be administered as either a single dose before a bout of acute exercise or in multiple doses (one before and three daily doses for the 4 days following the acute exercise). We hypothesize that HMB in free acid gel will result in less muscle damage, diminished inflammatory response, and improved muscle strength recovery than either a placebo or CaHMB treatment following a bout of acute eccentric exercise. Our endpoints will include measurements of: (1) markers for muscle damage (CPK and LDH); (2) indicators of inflammation (CRP, TNF-α, IL-6, IL-1ra and IL-18); and (3) muscle strength recovery and soreness.

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT CaHMB
  • DIETARY_SUPPLEMENT HMB Free Acid Gel
  • DIETARY_SUPPLEMENT Placebo Gel Dosage

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2010-10
Est. Completion 2012-07
Phase Phase 1

Sponsor

Metabolic Technologies

16 total trials

What the Registry Record Tells You About NCT01150526

The ClinicalTrials.gov registry entry for NCT01150526 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Metabolic Technologies, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT01150526 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01150526 about?

NCT01150526 is a clinical study titled "Efficacy of a New Delivery System for Beta-hydroxy-beta-methylbutyrate". The proposed study will test efficacy of HMB in free acid gel to decrease muscle damage, diminish inflammatory response, and improve muscle strength recovery following an acute exercise stress. HMB in a free acid gel or in CaHMB capsule form will be administered as either a single dose before a bout...

What is the current status of trial NCT01150526?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2010-10. Estimated completion is 2012-07.

What interventions are being tested in trial NCT01150526?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), CaHMB (DIETARY_SUPPLEMENT), HMB Free Acid Gel (DIETARY_SUPPLEMENT), Placebo Gel Dosage (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01150526?

This trial is sponsored by Metabolic Technologies, which has 16 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.