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NCT01149915 · ClinicalTrials.gov registry record · Phase 1
Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias
A Phase 1 study, sponsored by Threshold Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT01149915: Completed Phase 1 study, sponsored by Threshold Pharmaceuticals.
NCT01149915 is a Phase 1 study that has completed, run by Threshold Pharmaceuticals. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01149915, a Phase 1 study, has completed, sponsored by Threshold Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
The primary objective of this study is to determine the maximum tolerated dose, dose limiting toxicity, safety and tolerability of TH-302 in patients with acute leukemias, advanced phase chronic myelogenous leukemia (CML), high risk myelodysplastic syndromes, advanced myelofibrosis or relapsed/refractory chronic lymphocytic leukemia (CLL).
Interventions
- DRUG TH-302
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2010-06 |
| Est. Completion | 2013-08 |
| Phase | Phase 1 |
What the finished NCT01149915 record still lists
NCT01149915 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 1 intervention - of which TH-302 is the first listed.
NCT01149915 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01149915 about?
NCT01149915 is a clinical study titled "Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias". The primary objective of this study is to determine the maximum tolerated dose, dose limiting toxicity, safety and tolerability of TH-302 in patients with acute leukemias, advanced phase chronic myelogenous leukemia (CML), high risk myelodysplastic syndromes, advanced myelofibrosis or relapsed/refra...
What is the current status of trial NCT01149915?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2010-06. Estimated completion is 2013-08.
What interventions are being tested in trial NCT01149915?
The interventions under investigation include: TH-302 (DRUG).
Who is sponsoring clinical trial NCT01149915?
This trial is sponsored by Threshold Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01149915's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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