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NCT01147588 · ClinicalTrials.gov registry record · Phase 1
Study Evaluating Effect of Esomeprazole, Omeprazole or Lansoprazole on the Pharmacodynamics (PD) and Pharmacokinetics (PK) of Clopidogrel
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 149
- Enrollment target
NCT01147588: Completed Phase 1 study, sponsored by AstraZeneca.
NCT01147588 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 149 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (148% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01147588, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 149 participants
- Enrollment target
Study Summary
The aim of this study is to determine if there is a pharmacological interaction between clopidogrel and different types of proton pump inhibitors (PPIs), and if the extent of this possible interaction would change over time.
Interventions
- DRUG esomeprazole
- DRUG clopidogrel
- DRUG lansoprazole
- DRUG omeprazole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 149 participants |
| Start Date | 2010-05 |
| Est. Completion | 2011-05 |
| Phase | Phase 1 |
What the finished NCT01147588 record still lists
NCT01147588 is an interventional study that assigns participants to a tested intervention. The registered 149 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (148% higher).
The record links to 0 conditions, and to 4 interventions - of which esomeprazole is the first listed.
NCT01147588 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01147588 about?
NCT01147588 is a clinical study titled "Study Evaluating Effect of Esomeprazole, Omeprazole or Lansoprazole on the Pharmacodynamics (PD) and Pharmacokinetics (PK) of Clopidogrel". The aim of this study is to determine if there is a pharmacological interaction between clopidogrel and different types of proton pump inhibitors (PPIs), and if the extent of this possible interaction would change over time.
What is the current status of trial NCT01147588?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 149 participants. The study started on 2010-05. Estimated completion is 2011-05.
What interventions are being tested in trial NCT01147588?
The interventions under investigation include: esomeprazole (DRUG), clopidogrel (DRUG), lansoprazole (DRUG), omeprazole (DRUG).
Who is sponsoring clinical trial NCT01147588?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01147588's enrollment target sits among peer trials
149 381st of 2000 higher than 1,619 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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