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NCT01145222 · ClinicalTrials.gov registry record · Phase 2
Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy
A Phase 2 study, sponsored by Paion UK.
- Completed
- Registry status
- Phase 2
- Development phase
- 162
- Enrollment target
NCT01145222: Completed Phase 2 study, sponsored by Paion UK.
NCT01145222 is a Phase 2 study that has completed, run by Paion UK. The registered enrollment target is 162 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (22% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01145222, a Phase 2 study, has completed, sponsored by Paion UK.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 162 participants
- Enrollment target
Study Summary
The purpose of this dose-response study is to assess the safety and efficacy of CNS 7056 compared with midazolam to maintain suitable sedation levels in patients undergoing colonoscopy.
Primary Outcome
Success of the procedure is a composite endpoint consisting of: Modified Observer's Assessment for Alertness/Sedation (MOAA/S) scores ≤4 on three consecutive measurements after administration of study drug AND completion of the endoscopy procedure AND no requirement for rescue sedative medication AND no requirement for manual or mechanical ventilation
Interventions
- DRUG A. CNS 7056
- DRUG B. CNS 7056
- DRUG C. CNS 7056
- DRUG D. Midazolam
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 162 participants |
| Start Date | 2010-05 |
| Est. Completion | 2010-10 |
| Phase | Phase 2 |
What the finished NCT01145222 record still lists
NCT01145222 is an interventional study that assigns participants to a tested intervention. The registered 162 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (22% higher).
The record links to 0 conditions, and to 4 interventions - of which A. CNS 7056 is the first listed.
NCT01145222 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01145222 about?
NCT01145222 is a clinical study titled "Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy". The purpose of this dose-response study is to assess the safety and efficacy of CNS 7056 compared with midazolam to maintain suitable sedation levels in patients undergoing colonoscopy.
What is the current status of trial NCT01145222?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 162 participants. The study started on 2010-05. Estimated completion is 2010-10.
What interventions are being tested in trial NCT01145222?
The interventions under investigation include: A. CNS 7056 (DRUG), B. CNS 7056 (DRUG), C. CNS 7056 (DRUG), D. Midazolam (DRUG).
Who is sponsoring clinical trial NCT01145222?
This trial is sponsored by Paion UK, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01145222's enrollment target sits among peer trials
162 418th of 2000 higher than 1,579 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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