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NCT01141244 · ClinicalTrials.gov registry record · Phase 1
Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors
A Phase 1 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
NCT01141244: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).
NCT01141244 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 72 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01141244, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
Study Summary
This phase I trial studies the side effects and the best dose of temsirolimus when given together with irinotecan hydrochloride and temozolomide in treating younger patients with recurrent or refractory solid tumors. Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as irinotecan hydrochloride and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving temsirolimus with combination chemotherapy may kill more tumor cells.
Interventions
- OTHER laboratory biomarker analysis
- DRUG temozolomide
- DRUG irinotecan hydrochloride
- DRUG temsirolimus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2010-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01141244
The ClinicalTrials.gov registry entry for NCT01141244 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.
NCT01141244 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01141244 about?
NCT01141244 is a clinical study titled "Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors". This phase I trial studies the side effects and the best dose of temsirolimus when given together with irinotecan hydrochloride and temozolomide in treating younger patients with recurrent or refractory solid tumors. Temsirolimus may stop the growth of tumor cells by blocking some of the enzymes nee...
What is the current status of trial NCT01141244?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2010-06.
What interventions are being tested in trial NCT01141244?
The interventions under investigation include: laboratory biomarker analysis (OTHER), temozolomide (DRUG), irinotecan hydrochloride (DRUG), temsirolimus (DRUG).
Who is sponsoring clinical trial NCT01141244?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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