Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01139996 · ClinicalTrials.gov registry record · Phase 4

Use of Transdermal Clonidine in Trauma Patients

A Phase 4 study, sponsored by Memorial Health University Medical Center.

Terminated
Registry status
Phase 4
Development phase
22
Enrollment target

NCT01139996: Clinical Trial Phase 4 study, sponsored by Memorial Health University Medical Center.

NCT01139996 is a Phase 4 study that was terminated before completion, run by Memorial Health University Medical Center. The registered enrollment target is 22 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01139996, a Phase 4 study, was terminated before completion, sponsored by Memorial Health University Medical Center.

TERMINATED
Registry status
Phase 4
Development phase
22 participants
Enrollment target

Study Summary

This study will attempt to learn how to better treat trauma patients with delirium who are on a breathing machine. Delirium, also known as acute, temporary brain dysfunction, is a common reason why ventilated patients can not be weaned from the breathing machine even though their lungs may be healthy enough to breathe without the machine. The study hopes to show that by decreasing the patient's delirium it will lead to quicker weaning from the breathing machine and possibly a quicker overall recovery as well. Patients enrolled in this study will be treated with Clonidine or placebo. Clonidine is a drug that produces significant calming effects, decreases anxiety, and reduces pain, but with a lower incidence of delirium than other medications used in the ICU for this purpose. Clonidine is not approved by the Federal Food and Drug Administration for treatment of delirium, but is commonly used for this purpose.

Primary Outcome

data were not collected

Interventions

  • DRUG Placebo
  • DRUG Clonidine

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2010-05
Est. Completion 2012-08
Phase Phase 4

Why NCT01139996 stopped before completion

NCT01139996 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01139996 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01139996 about?

NCT01139996 is a clinical study titled "Use of Transdermal Clonidine in Trauma Patients". This study will attempt to learn how to better treat trauma patients with delirium who are on a breathing machine. Delirium, also known as acute, temporary brain dysfunction, is a common reason why ventilated patients can not be weaned from the breathing machine even though their lungs may be health...

What is the current status of trial NCT01139996?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 22 participants. The study started on 2010-05. Estimated completion is 2012-08.

What interventions are being tested in trial NCT01139996?

The interventions under investigation include: Placebo (DRUG), Clonidine (DRUG).

Who is sponsoring clinical trial NCT01139996?

This trial is sponsored by Memorial Health University Medical Center, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01139996's enrollment target sits among peer trials

22 1731st of 2000 higher than 259 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02508038 · 22 participants · Phase 1

    Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

  • NCT03099356 · 22 participants · Phase 2

    Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer

  • NCT03676647 · 22 participants

    Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

  • NCT04569591 · 22 participants · NA

    DDAVP for Pituitary Adenoma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01139996, the US trial registry maintained by the National Library of Medicine. NCT01139996 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.