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NCT01128413 · ClinicalTrials.gov registry record · NA
Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)
A NA study, sponsored by Washington University School of Medicine.
- Terminated
- Registry status
- NA
- Development phase
- 22
- Enrollment target
NCT01128413: Clinical Trial NA study, sponsored by Washington University School of Medicine.
NCT01128413 is a NA study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 22 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01128413, a NA study, was terminated before completion, sponsored by Washington University School of Medicine.
- TERMINATED
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
Study Summary
The short term goal of this study is to evaluate a non-invasive approach that optimizes intravenous (IV) fluid administration according to heart performance and results in surrogate improvements in morbidity and mortality via lactate clearance. Additional objectives include comparative assessments of methods for determining volume responsiveness and establishing a prevalence of volume responsive shock in the Emergency Department (ED).
Primary Outcome
The median lactate clearance from time zero to within 6 hours of the ED stay.
Interventions
- DEVICE Cheetah NICOM® PLRT
- DEVICE USCOM ® (Ultrasound Cardiac Output Monitor)
- DEVICE Inferior Vena Cava (IVC) Ultrasound Collapsibility
- BEHAVIORAL CURVES Questionnaire
- BIOLOGICAL Lactate Clearance
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2010-07 |
| Est. Completion | 2013-11 |
| Phase | NA |
Why NCT01128413 stopped before completion
NCT01128413 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 5 interventions - of which Cheetah NICOM® PLRT is the first listed.
NCT01128413 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01128413 about?
NCT01128413 is a clinical study titled "Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)". The short term goal of this study is to evaluate a non-invasive approach that optimizes intravenous (IV) fluid administration according to heart performance and results in surrogate improvements in morbidity and mortality via lactate clearance. Additional objectives include comparative assessments o...
What is the current status of trial NCT01128413?
This trial is currently terminated. It is a NA study. The enrollment target is 22 participants. The study started on 2010-07. Estimated completion is 2013-11.
What interventions are being tested in trial NCT01128413?
The interventions under investigation include: Cheetah NICOM® PLRT (DEVICE), USCOM ® (Ultrasound Cardiac Output Monitor) (DEVICE), Inferior Vena Cava (IVC) Ultrasound Collapsibility (DEVICE), CURVES Questionnaire (BEHAVIORAL), Lactate Clearance (BIOLOGICAL).
Who is sponsoring clinical trial NCT01128413?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01128413's enrollment target sits among peer trials
22 1756th of 2000 higher than 239 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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