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NCT01128335 · ClinicalTrials.gov registry record · Phase 2

Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-tacrolimus in de Novo Liver Transplant Patients

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
200
Enrollment target

NCT01128335 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 200 participants.

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The verdict

NCT01128335, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
200 participants
Enrollment target

Study Summary

This study will assess the safety and efficacy of different doses of sotrastaurin when combined with tacrolimus for the prevention of acute rejection after de novo liver transplantation.

Interventions

  • DRUG MMF(1000mg bid) + tacrolimus + standard of care medications
  • DRUG sotrastaurin (200mg bid) + tacrolimus + standard of care medications
  • DRUG sotrastaurin (300 mg bid) + tacrolimus + standard of care medications

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2010-04
Est. Completion 2012-07
Phase Phase 2

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT01128335

The ClinicalTrials.gov registry entry for NCT01128335 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which MMF(1000mg bid) + tacrolimus + standard of care medications is the first listed.

NCT01128335 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01128335 about?

NCT01128335 is a clinical study titled "Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-tacrolimus in de Novo Liver Transplant Patients". This study will assess the safety and efficacy of different doses of sotrastaurin when combined with tacrolimus for the prevention of acute rejection after de novo liver transplantation.

What is the current status of trial NCT01128335?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2010-04. Estimated completion is 2012-07.

What interventions are being tested in trial NCT01128335?

The interventions under investigation include: MMF(1000mg bid) + tacrolimus + standard of care medications (DRUG), sotrastaurin (200mg bid) + tacrolimus + standard of care medications (DRUG), sotrastaurin (300 mg bid) + tacrolimus + standard of care medications (DRUG).

Who is sponsoring clinical trial NCT01128335?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.