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NCT01128049 · ClinicalTrials.gov registry record · NA
Non-invasive Tear Film Dynamic Measurements in Normal, MGD and ADDE Subjects After Saline Instillation
A NA study, sponsored by University of Rochester.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT01128049: Completed NA study, sponsored by University of Rochester.
NCT01128049 is a NA study that has completed, run by University of Rochester. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01128049, a NA study, has completed, sponsored by University of Rochester.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Compare the objective tear film dynamic measurements in three different populations (MGD \[Meibomium Gland Dysfunction\], ADDE \[Aqueous Deficient Dry Eye\] and normal/control \[non-dry eye\]) and the subjective experience before and after instilling a single drop of saline in each eye. Currently available office-based tests for dry eye do not reliably correlate with patients' subjective symptoms. This study is interested in assessing how individuals with these two different ocular surface diseases compare with the normal population when measured objectively using two different instruments.
Primary Outcome
Average visual quality change over a 5 second blink cycle caused by movement of the tears over the surface of the eye by measuring optical irregularities.
Interventions
- BEHAVIORAL Subjective Questionnaire
- PROCEDURE Measurement with wavefront sensor (right eye, then left eye)
- DRUG Instill Saline Drop
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2010-06 |
| Est. Completion | 2011-12 |
| Phase | NA |
What the finished NCT01128049 record still lists
NCT01128049 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Subjective Questionnaire is the first listed.
NCT01128049 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01128049 about?
NCT01128049 is a clinical study titled "Non-invasive Tear Film Dynamic Measurements in Normal, MGD and ADDE Subjects After Saline Instillation". Compare the objective tear film dynamic measurements in three different populations (MGD \[Meibomium Gland Dysfunction\], ADDE \[Aqueous Deficient Dry Eye\] and normal/control \[non-dry eye\]) and the subjective experience before and after instilling a single drop of saline in each eye. Currently a...
What is the current status of trial NCT01128049?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2010-06. Estimated completion is 2011-12.
What interventions are being tested in trial NCT01128049?
The interventions under investigation include: Subjective Questionnaire (BEHAVIORAL), Measurement with wavefront sensor (right eye, then left eye) (PROCEDURE), Instill Saline Drop (DRUG).
Who is sponsoring clinical trial NCT01128049?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01128049's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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