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NCT01127399 · ClinicalTrials.gov registry record
Bariatric and Obstructive Lung Disease Study II
A clinical trial, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- 40
- Enrollment target
NCT01127399: Clinical Trial study, sponsored by Johns Hopkins University.
NCT01127399 is a clinical trial that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 40 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01127399 was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- 40 participants
- Enrollment target
Study Summary
The prevalence of obesity and asthma has significantly increased over the past two decades. The purpose of this study is to try and understand the mechanism by which obesity leads to airway hyperresponsiveness (AHR), one of the defining features of asthma. This research is being done to determine how weight or body size affects airway size and airway smooth muscle (ASM) tone and function. The goal of the study will be to look at if and how, weight might affect lung functioning. The investigators hypothesize that low lung volumes in obesity lead to AHR by reducing airway caliber causing increased ASM tone with impairment in deep inspiration (DI) response similar to what is seen in asthma.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2009-09 |
| Est. Completion | 2011-06 |
Why NCT01127399 stopped before completion
NCT01127399 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01127399 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01127399 about?
NCT01127399 is a clinical study titled "Bariatric and Obstructive Lung Disease Study II". The prevalence of obesity and asthma has significantly increased over the past two decades. The purpose of this study is to try and understand the mechanism by which obesity leads to airway hyperresponsiveness (AHR), one of the defining features of asthma. This research is being done to determine ho...
What is the current status of trial NCT01127399?
This trial is currently terminated. The enrollment target is 40 participants. The study started on 2009-09. Estimated completion is 2011-06.
Who is sponsoring clinical trial NCT01127399?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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