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NCT01126333 · ClinicalTrials.gov registry record
Long-term Follow-up of Spare the Nephron (STN) Patients
A clinical trial, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- 128
- Enrollment target
NCT01126333 is a clinical trial that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 128 participants.
The verdict
NCT01126333 has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- 128 participants
- Enrollment target
Study Summary
Allograft nephropathy is the most common cause of allograft failure following kidney transplantation. Among putative etiologies, cumulative exposure to calcineurin inhibitors may be one of the important progression factors. "Spare the Nephron"(STN) is a unique study. Patients were randomized to either continue center-specific Calcinerium Inhibitor (CNI) therapy or have CNI replaced with sirolimus within the first six months after transplantation. Approximately 305 patients were enrolled in the study. More than 230 patients finished 2 years of follow-up. There was better patient and graft survival in those converted to sirolimus. There was also a 10% improvement in the kidney function of those who were converted. In this cohort, we wish to explore the durability of this improvement.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2010-06 |
| Est. Completion | 2015-06-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01126333
The ClinicalTrials.gov registry entry for NCT01126333 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 128 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01126333 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01126333 about?
NCT01126333 is a clinical study titled "Long-term Follow-up of Spare the Nephron (STN) Patients". Allograft nephropathy is the most common cause of allograft failure following kidney transplantation. Among putative etiologies, cumulative exposure to calcineurin inhibitors may be one of the important progression factors. "Spare the Nephron"(STN) is a unique study. Patients were randomized to eit...
What is the current status of trial NCT01126333?
This trial is currently completed. The enrollment target is 128 participants. The study started on 2010-06. Estimated completion is 2015-06-30.
Who is sponsoring clinical trial NCT01126333?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
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