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NCT01126333 · ClinicalTrials.gov registry record
Long-term Follow-up of Spare the Nephron (STN) Patients
A clinical trial, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- 128
- Enrollment target
NCT01126333: Completed study, sponsored by University of Maryland, Baltimore.
NCT01126333 is a clinical trial that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 128 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01126333 has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- 128 participants
- Enrollment target
Study Summary
Allograft nephropathy is the most common cause of allograft failure following kidney transplantation. Among putative etiologies, cumulative exposure to calcineurin inhibitors may be one of the important progression factors. "Spare the Nephron"(STN) is a unique study. Patients were randomized to either continue center-specific Calcinerium Inhibitor (CNI) therapy or have CNI replaced with sirolimus within the first six months after transplantation. Approximately 305 patients were enrolled in the study. More than 230 patients finished 2 years of follow-up. There was better patient and graft survival in those converted to sirolimus. There was also a 10% improvement in the kidney function of those who were converted. In this cohort, we wish to explore the durability of this improvement.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2010-06 |
| Est. Completion | 2015-06-30 |
What the finished NCT01126333 record still lists
NCT01126333 is an observational study that tracks outcomes without assigning an intervention. The registered 128 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01126333 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01126333 about?
NCT01126333 is a clinical study titled "Long-term Follow-up of Spare the Nephron (STN) Patients". Allograft nephropathy is the most common cause of allograft failure following kidney transplantation. Among putative etiologies, cumulative exposure to calcineurin inhibitors may be one of the important progression factors. "Spare the Nephron"(STN) is a unique study. Patients were randomized to eit...
What is the current status of trial NCT01126333?
This trial is currently completed. The enrollment target is 128 participants. The study started on 2010-06. Estimated completion is 2015-06-30.
Who is sponsoring clinical trial NCT01126333?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
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