Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01117428 · ClinicalTrials.gov registry record · Phase 1

Sym004 in Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by Symphogen A/S.

Completed
Registry status
Phase 1
Development phase
111
Enrollment target

NCT01117428: Completed Phase 1 study, sponsored by Symphogen A/S.

NCT01117428 is a Phase 1 study that has completed, run by Symphogen A/S. The registered enrollment target is 111 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01117428, a Phase 1 study, has completed, sponsored by Symphogen A/S.

COMPLETED
Registry status
Phase 1
Development phase
111 participants
Enrollment target

Study Summary

This trial is designed as a multi-centre, open label, dose-escalation, phase I trial and consists of five parts.

Primary Outcome

The AEs were used as a primary endpoint. AEs were summarized using descriptive statistics and presented overall by system organ class and preferred term. The frequencies of AEs were presented including number and percentages of participants with events and the total number of events.

Interventions

  • DRUG Sym004

Trial Details

FieldValue
Enrollment Target 111 participants
Start Date 2010-03
Est. Completion 2015-05
Phase Phase 1
Symphogen A/S

12 total trials

What the finished NCT01117428 record still lists

NCT01117428 is an interventional study that assigns participants to a tested intervention. The registered 111 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% higher).

The record links to 0 conditions, and to 1 intervention - of which Sym004 is the first listed.

NCT01117428 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01117428 about?

NCT01117428 is a clinical study titled "Sym004 in Patients With Advanced Solid Tumors". This trial is designed as a multi-centre, open label, dose-escalation, phase I trial and consists of five parts.

What is the current status of trial NCT01117428?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 111 participants. The study started on 2010-03. Estimated completion is 2015-05.

What interventions are being tested in trial NCT01117428?

The interventions under investigation include: Sym004 (DRUG).

Who is sponsoring clinical trial NCT01117428?

This trial is sponsored by Symphogen A/S, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01117428's enrollment target sits among peer trials

111 512th of 2000 higher than 1,487 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03875716 · 111 participants · NA

    Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

  • NCT04693468 · 111 participants · Phase 1

    Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

  • NCT05263050 · 111 participants · Phase 2

    Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

  • NCT05600842 · 111 participants

    De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01117428, the US trial registry maintained by the National Library of Medicine. NCT01117428 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.