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NCT01117181 · ClinicalTrials.gov registry record · Phase 2
Apathy in Dementia Methylphenidate Trial (ADMET)
A Phase 2 study, sponsored by Johns Hopkins Bloomberg School of Public Health.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT01117181: Completed Phase 2 study, sponsored by Johns Hopkins Bloomberg School of Public Health.
NCT01117181 is a Phase 2 study that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01117181, a Phase 2 study, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
The Apathy in Dementia Methylphenidate Trial (ADMET) is a masked, placebo-controlled trial that will examine the efficacy and safety of methylphenidate for the treatment of clinically significant apathy in patients with Alzheimer's dementia.
Primary Outcome
Change in score of Apathy Evaluation Scale from baseline to 6 weeks; the minimum score is 18; the maximum score is 72. Higher scores indicate more severe apathy.
Interventions
- DRUG placebo
- DRUG Methylphenidate
- OTHER Psychosocial intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2010-06 |
| Est. Completion | 2012-08 |
| Phase | Phase 2 |
What the finished NCT01117181 record still lists
NCT01117181 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT01117181 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01117181 about?
NCT01117181 is a clinical study titled "Apathy in Dementia Methylphenidate Trial (ADMET)". The Apathy in Dementia Methylphenidate Trial (ADMET) is a masked, placebo-controlled trial that will examine the efficacy and safety of methylphenidate for the treatment of clinically significant apathy in patients with Alzheimer's dementia.
What is the current status of trial NCT01117181?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2010-06. Estimated completion is 2012-08.
What interventions are being tested in trial NCT01117181?
The interventions under investigation include: placebo (DRUG), Methylphenidate (DRUG), Psychosocial intervention (OTHER).
Who is sponsoring clinical trial NCT01117181?
This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01117181's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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