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NCT01115452 · ClinicalTrials.gov registry record · Phase 2
Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
A Phase 2 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 2
- Development phase
- 32
- Enrollment target
NCT01115452: Completed Phase 2 study, sponsored by GlaxoSmithKline.
NCT01115452 is a Phase 2 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 32 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (76% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01115452, a Phase 2 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 32 participants
- Enrollment target
Study Summary
An exploratory study investigating the direct application of potassium nitrate (KNO3) solutions of different concentrations in reducing dentine hypersensitivity.
Primary Outcome
Response to a one second application of air from a standard dental unit syringe applied to the surface of hypersensitive tooth. After each stimuli participant rated the intensity of pain on a 100 millimeter VAS, on which 0 represented "no pain" and 100 represented the" worst pain imaginable". Change from baseline was calculated as mean score at the given time point minus mean score at baseline.
Interventions
- OTHER Sterile water
- DRUG 5% Potassium nitrate
- DRUG 2.5% Potassium nitrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2009-09 |
| Est. Completion | 2009-10 |
| Phase | Phase 2 |
What the finished NCT01115452 record still lists
NCT01115452 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (76% lower).
The record links to 0 conditions, and to 3 interventions - of which Sterile water is the first listed.
NCT01115452 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01115452 about?
NCT01115452 is a clinical study titled "Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity". An exploratory study investigating the direct application of potassium nitrate (KNO3) solutions of different concentrations in reducing dentine hypersensitivity.
What is the current status of trial NCT01115452?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2009-09. Estimated completion is 2009-10.
What interventions are being tested in trial NCT01115452?
The interventions under investigation include: Sterile water (OTHER), 5% Potassium nitrate (DRUG), 2.5% Potassium nitrate (DRUG).
Who is sponsoring clinical trial NCT01115452?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01115452's enrollment target sits among peer trials
32 1563rd of 2000 higher than 423 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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