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NCT01114997 · ClinicalTrials.gov registry record · Phase 4
Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
A Phase 4 study, sponsored by Cedars-Sinai Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 32
- Enrollment target
NCT01114997: Clinical Trial Phase 4 study, sponsored by Cedars-Sinai Medical Center.
NCT01114997 is a Phase 4 study that was terminated before completion, run by Cedars-Sinai Medical Center. The registered enrollment target is 32 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01114997, a Phase 4 study, was terminated before completion, sponsored by Cedars-Sinai Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 32 participants
- Enrollment target
Study Summary
The purpose of this prospective, randomized, double-blinded, active-controlled study is: To assess the effectiveness of systemic administration of lidocaine and esmolol in combination (vs. either drug alone) will result in improved postoperative outcomes for patients undergoing abdominal surgery (e.g., less pain and postoperative constipation, nausea and vomiting, faster return of bowel function, resumption of normal activities of daily living), leading to a shorten length of hospital stay, maintaining hemodynamic stability during general anesthesia, when administered as intravenous adjuvants
Primary Outcome
Outcome had a duration of one day at post-anesthesia care unit (PACU) Postoperative pain measured using a Verbal Rating Scale (VRS) Postoperative pain VRS scores: 0 = none pain to 10 = intolerable pain.
Interventions
- DRUG Lidocaine
- DRUG Esmolol
- DRUG Lidocaine + Esmolol (Combo)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2010-04 |
| Est. Completion | 2015-06 |
| Phase | Phase 4 |
Why NCT01114997 stopped before completion
NCT01114997 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 3 interventions - of which Lidocaine is the first listed.
NCT01114997 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01114997 about?
NCT01114997 is a clinical study titled "Effect of Lidocaine and Esmolol to Improve the Quality of Recovery". The purpose of this prospective, randomized, double-blinded, active-controlled study is: To assess the effectiveness of systemic administration of lidocaine and esmolol in combination (vs. either drug alone) will result in improved postoperative outcomes for patients undergoing abdominal surgery (e...
What is the current status of trial NCT01114997?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2010-04. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01114997?
The interventions under investigation include: Lidocaine (DRUG), Esmolol (DRUG), Lidocaine + Esmolol (Combo) (DRUG).
Who is sponsoring clinical trial NCT01114997?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01114997's enrollment target sits among peer trials
32 1534th of 2000 higher than 457 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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