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NCT01107301 · ClinicalTrials.gov registry record

Vascular Effects of Attention Deficit Hyperactivity Disorder (ADHD) Medications in Youth

A clinical trial, sponsored by University of Minnesota.

Completed
Registry status
138
Enrollment target

NCT01107301 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 138 participants.

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The verdict

NCT01107301 has completed, sponsored by University of Minnesota.

COMPLETED
Registry status
138 participants
Enrollment target

Study Summary

4.4 million children and adolescents in the United States have been diagnosed with attention deficit hyperactivity disorder (ADHD) and more than half are treated with medication. Most ADHD medications are stimulants, which activate the sympathetic nervous system (SNS). SNS activation is closely associated with vascular functional and mechanical abnormalities. Therefore, ADHD medications, via instigating SNS activation and altering the hemodynamic profile, may have untoward effects on the vasculature and increase risk of developing cardiovascular disease in children and adolescents who use them. Our overall objective in this study is to determine whether ADHD medication use is associated SNS activation, endothelial dysfunction, and arterial stiffness in children and adolescents. We will address this objective by conducting a case-control study and obtain non-invasive measures of SNS activation, endothelial function, and arterial stiffness in children and adolescents (8-17 years old) with (using stimulant medication) and without ADHD.

Trial Details

FieldValue
Enrollment Target 138 participants
Start Date 2010-01
Est. Completion 2013-07

Sponsor

University of Minnesota

966 total trials

What the Registry Record Tells You About NCT01107301

The ClinicalTrials.gov registry entry for NCT01107301 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 138 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT01107301 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01107301 about?

NCT01107301 is a clinical study titled "Vascular Effects of Attention Deficit Hyperactivity Disorder (ADHD) Medications in Youth". 4.4 million children and adolescents in the United States have been diagnosed with attention deficit hyperactivity disorder (ADHD) and more than half are treated with medication. Most ADHD medications are stimulants, which activate the sympathetic nervous system (SNS). SNS activation is closely asso...

What is the current status of trial NCT01107301?

This trial is currently completed. The enrollment target is 138 participants. The study started on 2010-01. Estimated completion is 2013-07.

Who is sponsoring clinical trial NCT01107301?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.