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NCT01107301 · ClinicalTrials.gov registry record
Vascular Effects of Attention Deficit Hyperactivity Disorder (ADHD) Medications in Youth
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 138
- Enrollment target
NCT01107301: Completed study, sponsored by University of Minnesota.
NCT01107301 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 138 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01107301 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 138 participants
- Enrollment target
Study Summary
4.4 million children and adolescents in the United States have been diagnosed with attention deficit hyperactivity disorder (ADHD) and more than half are treated with medication. Most ADHD medications are stimulants, which activate the sympathetic nervous system (SNS). SNS activation is closely associated with vascular functional and mechanical abnormalities. Therefore, ADHD medications, via instigating SNS activation and altering the hemodynamic profile, may have untoward effects on the vasculature and increase risk of developing cardiovascular disease in children and adolescents who use them. Our overall objective in this study is to determine whether ADHD medication use is associated SNS activation, endothelial dysfunction, and arterial stiffness in children and adolescents. We will address this objective by conducting a case-control study and obtain non-invasive measures of SNS activation, endothelial function, and arterial stiffness in children and adolescents (8-17 years old) with (using stimulant medication) and without ADHD.
Primary Outcome
Carotid-radial pulse wave velocity and aortic augmentation index.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2010-01 |
| Est. Completion | 2013-07 |
What the finished NCT01107301 record still lists
NCT01107301 is an observational study that tracks outcomes without assigning an intervention. The registered 138 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01107301 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01107301 about?
NCT01107301 is a clinical study titled "Vascular Effects of Attention Deficit Hyperactivity Disorder (ADHD) Medications in Youth". 4.4 million children and adolescents in the United States have been diagnosed with attention deficit hyperactivity disorder (ADHD) and more than half are treated with medication. Most ADHD medications are stimulants, which activate the sympathetic nervous system (SNS). SNS activation is closely asso...
What is the current status of trial NCT01107301?
This trial is currently completed. The enrollment target is 138 participants. The study started on 2010-01. Estimated completion is 2013-07.
Who is sponsoring clinical trial NCT01107301?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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