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NCT01102803 · ClinicalTrials.gov registry record · Phase 3

D-Cycloserine to Enhance Cognitive Behavioral Therapy (CBT) for Acrophobia

A Phase 3 study, sponsored by Southern Methodist University.

Completed
Registry status
Phase 3
Development phase
40
Enrollment target

NCT01102803: Completed Phase 3 study, sponsored by Southern Methodist University.

NCT01102803 is a Phase 3 study that has completed, run by Southern Methodist University. The registered enrollment target is 40 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01102803, a Phase 3 study, has completed, sponsored by Southern Methodist University.

COMPLETED
Registry status
Phase 3
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this study is to investigate the utility of post-session administration of D-cycloserine to enhance fear extinction in a sample of people with acrophobia who will be treated with CBT.

Primary Outcome

Self-report measure that assesses fear and avoidance of a variety of heights situations. This questionnaire (Cohen, 1977) describes 20 situations and assesses levels of avoidance (0-3) and anxiety (0-6). These scales widely used measure of acrophobia with adequate retest reliability (r = .82-.86) and validity (Baker et al., 1973). Higher scores indicate higher levels of avoidance/anxiety (i.e., worse outcome). All subscales are summed for a total score. AAVQ will be assessed at each visit throug

Interventions

  • DRUG Placebo
  • DRUG D-Cycloserine
  • BEHAVIORAL Individual Cognitive Behavioral Therapy (CBT)

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2010-04
Est. Completion 2011-07
Phase Phase 3
Southern Methodist University

17 total trials

What the finished NCT01102803 record still lists

NCT01102803 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT01102803 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01102803 about?

NCT01102803 is a clinical study titled "D-Cycloserine to Enhance Cognitive Behavioral Therapy (CBT) for Acrophobia". The purpose of this study is to investigate the utility of post-session administration of D-cycloserine to enhance fear extinction in a sample of people with acrophobia who will be treated with CBT.

What is the current status of trial NCT01102803?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 40 participants. The study started on 2010-04. Estimated completion is 2011-07.

What interventions are being tested in trial NCT01102803?

The interventions under investigation include: Placebo (DRUG), D-Cycloserine (DRUG), Individual Cognitive Behavioral Therapy (CBT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT01102803?

This trial is sponsored by Southern Methodist University, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01102803's enrollment target sits among peer trials

40 1878th of 2000 higher than 103 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01102803, the US trial registry maintained by the National Library of Medicine. NCT01102803 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.