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NCT01094574 · ClinicalTrials.gov registry record · NA
Evaluation of Propranolol's Effect on Pain and Inflammation.
A NA study, sponsored by Martin Angst.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT01094574: Completed NA study, sponsored by Martin Angst.
NCT01094574 is a NA study that has completed, run by Martin Angst. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01094574, a NA study, has completed, sponsored by Martin Angst.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Previous studies have shown that the beta-adrenergic system plays a role in processing pain and the expression of hyperalgesia. Recent studies have investigated the analgesic effects, and potential anti-hyperalgesic effects (using a model of opioid induced (OIH) hyperalgesia) of propranolol, a beta adrenergic antagonist. We plan to further investigate the analgesic effects, and the potential anti inflammatory effects, of propranolol and compare those effects to alfentanil, an opioid of known effect, and placebo
Primary Outcome
Degrees Centigrade Heat pain was induced with a thermal sensory analyzer (TSA-II, Medoc Advanced Medical Systems, Durham, North Carolina). A thermode was placed in contact with skin on the upper thigh. Starting at a comfortable temperature, the thermode temperature was increased at a measured rate. Study participants pushed a button of a hand-held device at the onset of pain at which point the thermode immediately reduced the temperature. Measurements for analgesia were taken at the sites of non
Interventions
- DRUG Placebo
- DRUG Propranolol
- DRUG Alfentanil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2010-01 |
| Est. Completion | 2010-08 |
| Phase | NA |
What the finished NCT01094574 record still lists
NCT01094574 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT01094574 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01094574 about?
NCT01094574 is a clinical study titled "Evaluation of Propranolol's Effect on Pain and Inflammation.". Previous studies have shown that the beta-adrenergic system plays a role in processing pain and the expression of hyperalgesia. Recent studies have investigated the analgesic effects, and potential anti-hyperalgesic effects (using a model of opioid induced (OIH) hyperalgesia) of propranolol, a beta ...
What is the current status of trial NCT01094574?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2010-01. Estimated completion is 2010-08.
What interventions are being tested in trial NCT01094574?
The interventions under investigation include: Placebo (DRUG), Propranolol (DRUG), Alfentanil (DRUG).
Who is sponsoring clinical trial NCT01094574?
This trial is sponsored by Martin Angst, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01094574's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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