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NCT01075464 · ClinicalTrials.gov registry record · Phase 1

A Study of the Safety and Pharmacology of MEGF0444A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advanced or Metastatic Solid Tumors

A Phase 1 study, sponsored by Genentech.

Completed
Registry status
Phase 1
Development phase
64
Enrollment target

NCT01075464 is a Phase 1 study that has completed, run by Genentech. The registered enrollment target is 64 participants.

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The verdict

NCT01075464, a Phase 1 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 1
Development phase
64 participants
Enrollment target

Study Summary

This is a Phase Ib, open-label, dose-escalation study of MEGF0444A in combination with bevacizumab, and in combination with bevacizumab and paclitaxel as therapy for locally advanced or metastatic solid tumors.

Interventions

  • DRUG bevacizumab
  • DRUG paclitaxel
  • DRUG MEGF0444A

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2010-02
Est. Completion 2013-04
Phase Phase 1

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT01075464

The ClinicalTrials.gov registry entry for NCT01075464 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 64 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which bevacizumab is the first listed.

NCT01075464 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01075464 about?

NCT01075464 is a clinical study titled "A Study of the Safety and Pharmacology of MEGF0444A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advanced or Metastatic Solid Tumors". This is a Phase Ib, open-label, dose-escalation study of MEGF0444A in combination with bevacizumab, and in combination with bevacizumab and paclitaxel as therapy for locally advanced or metastatic solid tumors.

What is the current status of trial NCT01075464?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 64 participants. The study started on 2010-02. Estimated completion is 2013-04.

What interventions are being tested in trial NCT01075464?

The interventions under investigation include: bevacizumab (DRUG), paclitaxel (DRUG), MEGF0444A (DRUG).

Who is sponsoring clinical trial NCT01075464?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.