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NCT01073410 · ClinicalTrials.gov registry record
Chitinases and Transforming Growth Factor Beta (TGFB) in Human Asthma
A clinical trial, sponsored by University of California, San Francisco.
- Completed
- Registry status
- 23
- Enrollment target
NCT01073410: Completed study, sponsored by University of California, San Francisco.
NCT01073410 is a clinical trial that has completed, run by University of California, San Francisco. The registered enrollment target is 23 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01073410 has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- 23 participants
- Enrollment target
Study Summary
The purpose of this study is to find out the roles of two specific gene families (the chitinase gene family and the TGFB family). We hypothesize that chitinases and TGFb pathway genes will be differentially expressed in the airways of non-asthmatic subjects and subjects with asthma. We further hypothesize that genetic variants in CHIT1, AMCase, and TGFb pathway genes that show associations with asthma and related phenotypes will change the expression and/or function of the protein of these genes in the airway in several ways, including the transcript numbers for full length genes and splice variants and, for the chitinase genes, the levels of chitinase activity in airway secretions.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2010-02 |
| Est. Completion | 2021-04 |
What the finished NCT01073410 record still lists
NCT01073410 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 23 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01073410 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01073410 about?
NCT01073410 is a clinical study titled "Chitinases and Transforming Growth Factor Beta (TGFB) in Human Asthma". The purpose of this study is to find out the roles of two specific gene families (the chitinase gene family and the TGFB family). We hypothesize that chitinases and TGFb pathway genes will be differentially expressed in the airways of non-asthmatic subjects and subjects with asthma. We further hypot...
What is the current status of trial NCT01073410?
This trial is currently completed. The enrollment target is 23 participants. The study started on 2010-02. Estimated completion is 2021-04.
Who is sponsoring clinical trial NCT01073410?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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