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NCT01070212 · ClinicalTrials.gov registry record · NA

Effects of Gum Chewing on Appetite and Digestion

A NA study, sponsored by Purdue University.

Completed
Registry status
NA
Development phase
60
Enrollment target

NCT01070212: Completed NA study, sponsored by Purdue University.

NCT01070212 is a NA study that has completed, run by Purdue University. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01070212, a NA study, has completed, sponsored by Purdue University.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target

Study Summary

One obvious property difference between energy-yielding beverages and solid foods is the oral mechanical processing required to prepare the two food forms for swallowing. Considerable human data are consistent with a contribution of mechanical stimulation to appetite suppression. However, no study has isolated this property and assessed its influence on ingestive behavior in humans. This is the aim of the present study. The null hypothesis is that food rheology will have no effect on these indices. The alternate hypothesis is that increased mechanical stimulation will result in stronger satiation/satiety and reduced energy intake. Further, it is hypothesized that the effects of mastication will be less evident in obese compared to lean individuals.

Primary Outcome

Effects of varying chewing intensity on self-rated hunger, fullness, desire to eat and thirst.

Interventions

  • OTHER soft gum
  • OTHER firm gum
  • OTHER no gum

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2010-02
Est. Completion 2012-01
Phase NA
Purdue University

141 total trials

What the finished NCT01070212 record still lists

NCT01070212 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 3 interventions - of which soft gum is the first listed.

NCT01070212 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01070212 about?

NCT01070212 is a clinical study titled "Effects of Gum Chewing on Appetite and Digestion". One obvious property difference between energy-yielding beverages and solid foods is the oral mechanical processing required to prepare the two food forms for swallowing. Considerable human data are consistent with a contribution of mechanical stimulation to appetite suppression. However, no study h...

What is the current status of trial NCT01070212?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2010-02. Estimated completion is 2012-01.

What interventions are being tested in trial NCT01070212?

The interventions under investigation include: soft gum (OTHER), firm gum (OTHER), no gum (OTHER).

Who is sponsoring clinical trial NCT01070212?

This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01070212's enrollment target sits among peer trials

60 1164th of 2000 higher than 745 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01070212, the US trial registry maintained by the National Library of Medicine. NCT01070212 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.