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NCT01060020 · ClinicalTrials.gov registry record · Phase 4
Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic Stenosis
A Phase 4 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
NCT01060020 is a Phase 4 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 20 participants.
The verdict
NCT01060020, a Phase 4 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
Study Summary
Pulmonary hypertension is common in patients with aortic stenosis and is associated with worse operative and long-term outcomes. Sildenafil has been shown to reduce pulmonary artery pressure and improve exercise performance in patients with left-sided heart failure, but this has not been tested in patients with aortic stenosis. We hypothesize that Sildenafil will produce a clinically significant decrease in pulmonary artery pressure in patients with severe aortic stenosis. The dose of Sildenafil that produces a significant decrease in pulmonary artery pressure will be safe and well tolerated in patients with and without a depressed ejection fraction.
Interventions
- DRUG Sildenafil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2010-01 |
| Est. Completion | 2011-10 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01060020
The ClinicalTrials.gov registry entry for NCT01060020 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Sildenafil is the first listed.
NCT01060020 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01060020 about?
NCT01060020 is a clinical study titled "Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic Stenosis". Pulmonary hypertension is common in patients with aortic stenosis and is associated with worse operative and long-term outcomes. Sildenafil has been shown to reduce pulmonary artery pressure and improve exercise performance in patients with left-sided heart failure, but this has not been tested in p...
What is the current status of trial NCT01060020?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2010-01. Estimated completion is 2011-10.
What interventions are being tested in trial NCT01060020?
The interventions under investigation include: Sildenafil (DRUG).
Who is sponsoring clinical trial NCT01060020?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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