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NCT01058876 · ClinicalTrials.gov registry record · Phase 1
Comparison of Low Yield Cigarettes in African Americans vs. Whites
A Phase 1 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 1
- Development phase
- 43
- Enrollment target
NCT01058876 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 43 participants.
The verdict
NCT01058876, a Phase 1 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 43 participants
- Enrollment target
Study Summary
The investigators' general hypothesis is that African-Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of nicotine and tobacco smoke toxins), while whites smoke more for negative reinforcement with a "trough-maintaining" pattern (avoiding withdrawal by maintaining more consistent nicotine levels throughout the day by means of a more regular smoking pattern). We, the investigators, believe that these patterns are linked to identifiable racial differences in nicotine pharmacology. For this study we hypothesize that if AAs behave more like nicotine "peak-seeker" while whites behave more like nicotine "trough-maintainers", that AAs will respond to switching from regular to low nicotine yield commercial cigarettes by smoking each cigarette relatively more intensively with a relatively smaller increase in daily cigarette consumption (cigarettes per day or CPD) as compared to whites.
Interventions
- DRUG Deuterated nicotine and cotinine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2009-12 |
| Est. Completion | 2013-01 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01058876
The ClinicalTrials.gov registry entry for NCT01058876 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Deuterated nicotine and cotinine is the first listed.
NCT01058876 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01058876 about?
NCT01058876 is a clinical study titled "Comparison of Low Yield Cigarettes in African Americans vs. Whites". The investigators' general hypothesis is that African-Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of nicotine and tobacco smoke toxins), while whites smoke more for ne...
What is the current status of trial NCT01058876?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2009-12. Estimated completion is 2013-01.
What interventions are being tested in trial NCT01058876?
The interventions under investigation include: Deuterated nicotine and cotinine (DRUG).
Who is sponsoring clinical trial NCT01058876?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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