Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01058434 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
43
Enrollment target

NCT01058434: Completed Phase 2 study, sponsored by Novartis Pharmaceuticals.

NCT01058434 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 43 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01058434, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
43 participants
Enrollment target

Study Summary

This study will evaluate safety and efficacy of TKI258 in patients with relapsed or refractory multiple myeloma

Interventions

  • DRUG TKI258

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2010-05
Est. Completion 2013-02
Phase Phase 2
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT01058434 record still lists

NCT01058434 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower).

The record links to 0 conditions, and to 1 intervention - of which TKI258 is the first listed.

NCT01058434 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01058434 about?

NCT01058434 is a clinical study titled "Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation". This study will evaluate safety and efficacy of TKI258 in patients with relapsed or refractory multiple myeloma

What is the current status of trial NCT01058434?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2010-05. Estimated completion is 2013-02.

What interventions are being tested in trial NCT01058434?

The interventions under investigation include: TKI258 (DRUG).

Who is sponsoring clinical trial NCT01058434?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01058434's enrollment target sits among peer trials

43 1332nd of 2000 higher than 662 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03726359 · 43 participants · Phase 1

    Phase I Study of Fractionated Stereotactic Radiation Therapy

  • NCT03850418 · 43 participants · Phase 2

    Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant

  • NCT04144023 · 43 participants · Phase 1

    A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

  • NCT04176718 · 43 participants · Phase 2

    Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01058434, the US trial registry maintained by the National Library of Medicine. NCT01058434 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.