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NCT01048879 · ClinicalTrials.gov registry record · Phase 4
Pharmacokinetics of Tamiflu® (Oseltamivir) in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)and or Continuous Venovenous Hemodialysis (CVVHD)
A Phase 4 study, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 4
- Development phase
- 15
- Enrollment target
NCT01048879: Completed Phase 4 study, sponsored by University of Michigan.
NCT01048879 is a Phase 4 study that has completed, run by University of Michigan. The registered enrollment target is 15 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01048879, a Phase 4 study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 15 participants
- Enrollment target
Study Summary
Critically ill patients with flu may receive a drug called oseltamivir. They may also receive medical therapies to support their lung function (extracorporeal membrane oxygenation; ECMO) and kidney function (continuous venovenous hemodialysis; CVVHD). CVVHD and ECMO may remove some oseltamivir from the bloodstream. The purpose of this study is to determine how much oseltamivir gets removed by CVVHD or ECMO in critically ill patients.
Primary Outcome
Oseltamivir Carboxylate Transmembrane Clearance by Continuous Venovenous Hemodialysis (Reported in mL/min).
Interventions
- PROCEDURE pharmacokinetic blood sampling
- PROCEDURE pharmacokinetic blood and dialysate sampling
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2009-10 |
| Est. Completion | 2010-01 |
| Phase | Phase 4 |
What the finished NCT01048879 record still lists
NCT01048879 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which pharmacokinetic blood sampling is the first listed.
NCT01048879 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01048879 about?
NCT01048879 is a clinical study titled "Pharmacokinetics of Tamiflu® (Oseltamivir) in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)and or Continuous Venovenous Hemodialysis (CVVHD)". Critically ill patients with flu may receive a drug called oseltamivir. They may also receive medical therapies to support their lung function (extracorporeal membrane oxygenation; ECMO) and kidney function (continuous venovenous hemodialysis; CVVHD). CVVHD and ECMO may remove some oseltamivir from ...
What is the current status of trial NCT01048879?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 15 participants. The study started on 2009-10. Estimated completion is 2010-01.
What interventions are being tested in trial NCT01048879?
The interventions under investigation include: pharmacokinetic blood sampling (PROCEDURE), pharmacokinetic blood and dialysate sampling (PROCEDURE).
Who is sponsoring clinical trial NCT01048879?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01048879's enrollment target sits among peer trials
15 1880th of 2000 higher than 100 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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