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NCT01046643 · ClinicalTrials.gov registry record · NA
Early Menopause Hormone Treatment and Cognition
A NA study of Menopausal Syndrome, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT01046643: Completed NA study of Menopausal Syndrome, sponsored by University of Michigan.
NCT01046643 is a NA study of Menopausal Syndrome that has completed, run by University of Michigan. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01046643, a NA study of Menopausal Syndrome, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to evaluate the neurobiological effects of hormone therapy (HT) in healthy early postmenopausal women. The studies proposed in this project seek to define the association between different hormone forms (estradiol only and progesterone only) versus placebo on brain functional measures. The functional measures will include the performance of the volunteers on a comprehensive neuropsychological testing battery, and the brain functional responses to episodic memory (verbal and non-verbal) challenges as well as emotional processing determined with functional magnetic resonance imaging (fMRI).
Primary Outcome
Measure the changes in brain activity in verbal tasks with hormone use (either estradiol or progesterone) versus placebo. The test is a deep and shallow verbal processing task, where the subjects are presented lists of words, one word at a time, and are asked to make one of 2 decisions about each list. One decision is whether each word is written in upper or lower case letters (shallow processing), and the other decision is whether each word denotes an abstract or concrete concept (deep process
Conditions Studied
Interventions
- DRUG Estradiol (E2)
- DRUG Progesterone (P10) x90
- DRUG Progesterone (P10) x10
Study Locations (1)
Michigan
- The University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2010-05 |
| Est. Completion | 2012-03 |
| Phase | NA |
What the finished NCT01046643 record still lists
NCT01046643 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Menopausal Syndrome appearing as the primary indexed condition, and to 3 interventions - of which Estradiol (E2) is the first listed.
NCT01046643 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT01046643 about?
NCT01046643 is a clinical study titled "Early Menopause Hormone Treatment and Cognition". The objective of this study is to evaluate the neurobiological effects of hormone therapy (HT) in healthy early postmenopausal women. The studies proposed in this project seek to define the association between different hormone forms (estradiol only and progesterone only) versus placebo on brain fun...
What is the current status of trial NCT01046643?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2010-05. Estimated completion is 2012-03.
What conditions does trial NCT01046643 study?
This clinical trial studies the following conditions: Menopausal Syndrome.
What interventions are being tested in trial NCT01046643?
The interventions under investigation include: Estradiol (E2) (DRUG), Progesterone (P10) x90 (DRUG), Progesterone (P10) x10 (DRUG).
Who is sponsoring clinical trial NCT01046643?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01046643 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01046643's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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