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NCT01046058 · ClinicalTrials.gov registry record · Phase 1

TMC435-TiDP16-C113: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of TMC435

A Phase 1 study, sponsored by Tibotec Pharmaceuticals, Ireland.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT01046058 is a Phase 1 study that has completed, run by Tibotec Pharmaceuticals, Ireland. The registered enrollment target is 23 participants.

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The verdict

NCT01046058, a Phase 1 study, has completed, sponsored by Tibotec Pharmaceuticals, Ireland.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

The purpose of the study is to investigate the effect of moderate and severe hepatic impairment on the pharmacokinetics of TMC435. Pharmacokinetics means how the drug is absorbed into the bloodstream, distributed in the body and eliminated from the body. In addition, the short-term safety and tolerability of TMC435 in participants with hepatic impairment will be determined. The results of this study will guide dose recommendations for TMC435 in patients with impaired liver function.

Interventions

  • DRUG TMC435

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2010-01
Est. Completion 2011-07
Phase Phase 1

Sponsor

Tibotec Pharmaceuticals, Ireland

16 total trials

What the Registry Record Tells You About NCT01046058

The ClinicalTrials.gov registry entry for NCT01046058 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Tibotec Pharmaceuticals, Ireland, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which TMC435 is the first listed.

NCT01046058 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01046058 about?

NCT01046058 is a clinical study titled "TMC435-TiDP16-C113: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of TMC435". The purpose of the study is to investigate the effect of moderate and severe hepatic impairment on the pharmacokinetics of TMC435. Pharmacokinetics means how the drug is absorbed into the bloodstream, distributed in the body and eliminated from the body. In addition, the short-term safety and tolera...

What is the current status of trial NCT01046058?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2010-01. Estimated completion is 2011-07.

What interventions are being tested in trial NCT01046058?

The interventions under investigation include: TMC435 (DRUG).

Who is sponsoring clinical trial NCT01046058?

This trial is sponsored by Tibotec Pharmaceuticals, Ireland, which has 16 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.