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NCT01031043 · ClinicalTrials.gov registry record · Phase 1
Topical Bethanechol for Improvement of Esophageal Dysmotility
A Phase 1 study, sponsored by Augusta University.
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT01031043: Completed Phase 1 study, sponsored by Augusta University.
NCT01031043 is a Phase 1 study that has completed, run by Augusta University. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01031043, a Phase 1 study, has completed, sponsored by Augusta University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
The purpose of this research project is to determine the effect of a drug called bethanechol on swallowing function in patients with Ineffective Esophageal Motility (IEM). This drug is FDA approved for use in treating other conditions, but not for the treatment of IEM. There is currently no approved therapy for the treatment of IEM. This information is important for the possible development of new ways of treating patients with IEM and for the effectiveness of topically applied Bethanechol on patients with IEM.
Primary Outcome
The index of contractile strength of the esophageal smooth muscle. The range of the index being 0 mmHg \*s\*cm to \>10,000 mmHg \*s\*cm where 0 represents no contractile strength. The index reflects the magnitude of distal esophageal contraction, taking into consideration the length, strength, and duration of the contraction.
Interventions
- DRUG Bethanechol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2009-11 |
| Est. Completion | 2012-04 |
| Phase | Phase 1 |
What the finished NCT01031043 record still lists
NCT01031043 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which Bethanechol is the first listed.
NCT01031043 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01031043 about?
NCT01031043 is a clinical study titled "Topical Bethanechol for Improvement of Esophageal Dysmotility". The purpose of this research project is to determine the effect of a drug called bethanechol on swallowing function in patients with Ineffective Esophageal Motility (IEM). This drug is FDA approved for use in treating other conditions, but not for the treatment of IEM. There is currently no approved...
What is the current status of trial NCT01031043?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2009-11. Estimated completion is 2012-04.
What interventions are being tested in trial NCT01031043?
The interventions under investigation include: Bethanechol (DRUG).
Who is sponsoring clinical trial NCT01031043?
This trial is sponsored by Augusta University, which has 106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01031043's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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