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NCT01018836 · ClinicalTrials.gov registry record · Phase 1
Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
A Phase 1 study, sponsored by Rutgers, The State University of New Jersey.
- Terminated
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT01018836: Clinical Trial Phase 1 study, sponsored by Rutgers, The State University of New Jersey.
NCT01018836 is a Phase 1 study that was terminated before completion, run by Rutgers, The State University of New Jersey. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01018836, a Phase 1 study, was terminated before completion, sponsored by Rutgers, The State University of New Jersey.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. Drugs, such as riluzole, may make tumor cells more sensitive to radiation therapy. Giving riluzole together with whole-brain radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of riluzole when given together with whole-brain radiation therapy in treating patients with brain metastases.
Interventions
- DRUG riluzole
- RADIATION whole-brain radiation therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2009-11 |
| Est. Completion | 2013-12 |
| Phase | Phase 1 |
Why NCT01018836 stopped before completion
NCT01018836 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 2 interventions - of which riluzole is the first listed.
NCT01018836 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01018836 about?
NCT01018836 is a clinical study titled "Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases". RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. Drugs, such as riluzole, may make tumor cells more sensitive to radiation therapy. Giving riluzole together with whole-brain radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effect...
What is the current status of trial NCT01018836?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2009-11. Estimated completion is 2013-12.
What interventions are being tested in trial NCT01018836?
The interventions under investigation include: riluzole (DRUG), whole-brain radiation therapy (RADIATION).
Who is sponsoring clinical trial NCT01018836?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01018836's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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