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NCT00997373 · ClinicalTrials.gov registry record · NA

Letrozole as a Treatment of Endometrial Cancer

A NA study, sponsored by University of California, Davis.

Completed
Registry status
NA
Development phase
43
Enrollment target

NCT00997373: Completed NA study, sponsored by University of California, Davis.

NCT00997373 is a NA study that has completed, run by University of California, Davis. The registered enrollment target is 43 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00997373, a NA study, has completed, sponsored by University of California, Davis.

COMPLETED
Registry status
NA
Development phase
43 participants
Enrollment target

Study Summary

Some cases of endometrial cancer are dependent on estrogen for their growth. Letrozole blocks estrogen production in the body. The purpose of this study is to determine if the investigators can predict which patients might benefit from Letrozole treatment by studying the many different forms of the estrogen receptor molecule that exist within the cancer tissues. To participate in this study, the patients must be 40 years of age or older and have biopsy-proven endometrial carcinoma, either well differentiated or moderately differentiated forms. Also, to be eligible to participate in this study, the patients need to be healthy enough to have a hysterectomy. If the patients are less than age 60, they will need a blood test (FSH) to confirm that they have gone into menopause.

Primary Outcome

Changes in %Ki67 staining cells by immunoperoxidase of paraffin embedded, formalin fixed tissue

Interventions

  • DRUG Letrozole

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2009-10
Est. Completion 2013-09
Phase NA
University of California, Davis

657 total trials

What the finished NCT00997373 record still lists

NCT00997373 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Letrozole is the first listed.

NCT00997373 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00997373 about?

NCT00997373 is a clinical study titled "Letrozole as a Treatment of Endometrial Cancer". Some cases of endometrial cancer are dependent on estrogen for their growth. Letrozole blocks estrogen production in the body. The purpose of this study is to determine if the investigators can predict which patients might benefit from Letrozole treatment by studying the many different forms of the ...

What is the current status of trial NCT00997373?

This trial is currently completed. It is a NA study. The enrollment target is 43 participants. The study started on 2009-10. Estimated completion is 2013-09.

What interventions are being tested in trial NCT00997373?

The interventions under investigation include: Letrozole (DRUG).

Who is sponsoring clinical trial NCT00997373?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00997373's enrollment target sits among peer trials

43 1435th of 2000 higher than 565 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00997373, the US trial registry maintained by the National Library of Medicine. NCT00997373 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.