Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00995514 · ClinicalTrials.gov registry record
Genotype Guided Comparison of Clopidogrel and Prasugrel Outcomes Study
A clinical trial, sponsored by Medco Health Solutions.
- Terminated
- Registry status
- 4,471
- Enrollment target
NCT00995514: Clinical Trial study, sponsored by Medco Health Solutions.
NCT00995514 is a clinical trial that was terminated before completion, run by Medco Health Solutions. The registered enrollment target is 4,471 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00995514 was terminated before completion, sponsored by Medco Health Solutions.
- TERMINATED
- Registry status
- 4,471 participants
- Enrollment target
Study Summary
The primary objective of this trial is to demonstrate the non-inferiority of clopidogrel compared to prasugrel over 6 months in cardiovascular disease patients when the clopidogrel cohort is limited to the estimated 70% of the population that are CYP2C19 extensive metabolizers. This protocol will examine the comparative effectiveness of these two strategies.
Primary Outcome
To assess the non-inferiority of clopidogrel therapy in patients with cardiovascular disease who are CYP2C19 extensive metabolizers (identified by genetic testing) compared to prasugrel therapy (non-genotyped) on the composite primary end point of cardiovascular death, hospitalization for acute coronary syndrome (nonfatal MI or unstable angina), nonfatal stroke or coronary revascularization
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,471 participants |
| Start Date | 2009-10 |
| Est. Completion | 2012-05 |
Why NCT00995514 stopped before completion
NCT00995514 is an observational study that tracks outcomes without assigning an intervention. Its 4,471 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT00995514 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00995514 about?
NCT00995514 is a clinical study titled "Genotype Guided Comparison of Clopidogrel and Prasugrel Outcomes Study". The primary objective of this trial is to demonstrate the non-inferiority of clopidogrel compared to prasugrel over 6 months in cardiovascular disease patients when the clopidogrel cohort is limited to the estimated 70% of the population that are CYP2C19 extensive metabolizers. This protocol will ex...
What is the current status of trial NCT00995514?
This trial is currently terminated. The enrollment target is 4,471 participants. The study started on 2009-10. Estimated completion is 2012-05.
Who is sponsoring clinical trial NCT00995514?
This trial is sponsored by Medco Health Solutions, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06252753 · 4,490 participants
Observational Study Protocol: LIVER-R
- NCT06533111 · 4,500 participants · NA
Improving Surgical Patient Outcomes Through Implementation of a SemiStructured Intraoperative Anesthesia Handoff Tool
- NCT06588452 · 4,500 participants
Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models
- NCT07165028 · 4,500 participants · Phase 3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia