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NCT00993291 · ClinicalTrials.gov registry record · Phase 1
Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)
A Phase 1 study, sponsored by Vanderbilt University.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT00993291: Completed Phase 1 study, sponsored by Vanderbilt University.
NCT00993291 is a Phase 1 study that has completed, run by Vanderbilt University. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00993291, a Phase 1 study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking. The investigators' hypothesis is: 1. Stimulation at 60 Hertz (Hz) is associated with improved gait with increased stride length and faster time on the Stand walk sit test. 2. There is no worsening of the Unified Parkinson's Disease Rating Scale (UPDRS) at 60 Hz.
Primary Outcome
Evaluation performed after DBS frequency setting changed for one hour, compared to the subject's baseline DBS frequency stride length
Interventions
- PROCEDURE Frequency change to 60 Hz
- PROCEDURE Frequency change to 130 Hz
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2009-11 |
| Est. Completion | 2011-08 |
| Phase | Phase 1 |
What the finished NCT00993291 record still lists
NCT00993291 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Frequency change to 60 Hz is the first listed.
NCT00993291 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00993291 about?
NCT00993291 is a clinical study titled "Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)". In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking. The investigators' hypothesis is: 1. Stimulation at 60 Hertz (Hz) is associated with impr...
What is the current status of trial NCT00993291?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2009-11. Estimated completion is 2011-08.
What interventions are being tested in trial NCT00993291?
The interventions under investigation include: Frequency change to 60 Hz (PROCEDURE), Frequency change to 130 Hz (PROCEDURE).
Who is sponsoring clinical trial NCT00993291?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00993291's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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