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NCT00992056 · ClinicalTrials.gov registry record · Phase 4
Nebivolol Versus Metoprolol: Sodium Sensitivity
A Phase 4 study, sponsored by University of Miami.
- Completed
- Registry status
- Phase 4
- Development phase
- 24
- Enrollment target
NCT00992056 is a Phase 4 study that has completed, run by University of Miami. The registered enrollment target is 24 participants.
The verdict
NCT00992056, a Phase 4 study, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 24 participants
- Enrollment target
Study Summary
Research objectives The objective of this randomized, placebo-controlled, 2 period crossover clinical trial is to determine the effects of nebivolol versus metoprolol on ambulatory blood pressure, the blood pressure response to dietary sodium loading, and renal handling of an acute sodium load in postmenopausal women with hypertension. Hypothesis Nebivolol will result in a blunted response of blood pressure to oral sodium administration and improved renal handling of an intravenous sodium load in comparison with metoprolol in hypertensive postmenopausal women. Research plan Study design The study consisted of a randomized crossover trial of the effects on sodium sensitivity and renal sodium handling of nebivolol versus metoprolol. All study procedures were carried out under the direct supervision of the Principal Investigator in the outpatient and inpatient research unit of the University of Miami Division of Clinical Pharmacology. Primary endpoint Change in 24-hour mean systolic blood pressure determined by 24-hour ambulatory blood pressure monitor (ABPM) from the final day of low sodium to the final day of high sodium in nebivolol versus metoprolol
Interventions
- DRUG Metoprolol
- DRUG nebivolol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2010-12 |
| Est. Completion | 2012-05 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00992056
The ClinicalTrials.gov registry entry for NCT00992056 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Metoprolol is the first listed.
NCT00992056 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00992056 about?
NCT00992056 is a clinical study titled "Nebivolol Versus Metoprolol: Sodium Sensitivity". Research objectives The objective of this randomized, placebo-controlled, 2 period crossover clinical trial is to determine the effects of nebivolol versus metoprolol on ambulatory blood pressure, the blood pressure response to dietary sodium loading, and renal handling of an acute sodium load in p...
What is the current status of trial NCT00992056?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2010-12. Estimated completion is 2012-05.
What interventions are being tested in trial NCT00992056?
The interventions under investigation include: Metoprolol (DRUG), nebivolol (DRUG).
Who is sponsoring clinical trial NCT00992056?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
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