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NCT00990795 · ClinicalTrials.gov registry record · Phase 1
Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery
A Phase 1 study, sponsored by The University of Texas Health Science Center, Houston.
- Terminated
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
NCT00990795: Clinical Trial Phase 1 study, sponsored by The University of Texas Health Science Center, Houston.
NCT00990795 is a Phase 1 study that was terminated before completion, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00990795, a Phase 1 study, was terminated before completion, sponsored by The University of Texas Health Science Center, Houston.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
Study Summary
Administration of cyclosporine has been found to have a myocardial protective effect, improving post-operative cardiac function in patients undergoing percutaneous coronary interventions by diminishing infarct size. The purpose of the proposed study is to conduct a randomized, controlled clinical trial in patients undergoing isolated valvular heart surgery, or coronary artery bypass surgery. Specifically the investigators will evaluate the cardio-protective effects of cyclosporine on post ischemic-arrest myocardium. The two factors will be treatment group and cyclosporine versus placebo.
Interventions
- DRUG saline solution
- DRUG cyclosporine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2010-04 |
| Est. Completion | 2010-10 |
| Phase | Phase 1 |
Why NCT00990795 stopped before completion
NCT00990795 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).
The record links to 0 conditions, and to 2 interventions - of which saline solution is the first listed.
NCT00990795 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00990795 about?
NCT00990795 is a clinical study titled "Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery". Administration of cyclosporine has been found to have a myocardial protective effect, improving post-operative cardiac function in patients undergoing percutaneous coronary interventions by diminishing infarct size. The purpose of the proposed study is to conduct a randomized, controlled clinical tr...
What is the current status of trial NCT00990795?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2010-04. Estimated completion is 2010-10.
What interventions are being tested in trial NCT00990795?
The interventions under investigation include: saline solution (DRUG), cyclosporine (DRUG).
Who is sponsoring clinical trial NCT00990795?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00990795's enrollment target sits among peer trials
72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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