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NCT00988611 · ClinicalTrials.gov registry record
Assisted Reproductive Technology (ART) Predictors Study
A clinical trial, sponsored by University of Oklahoma.
- Completed
- Registry status
- 138
- Enrollment target
NCT00988611: Completed study, sponsored by University of Oklahoma.
NCT00988611 is a clinical trial that has completed, run by University of Oklahoma. The registered enrollment target is 138 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00988611 has completed, sponsored by University of Oklahoma.
- COMPLETED
- Registry status
- 138 participants
- Enrollment target
Study Summary
The goals of this research proposal are to further our understanding of the reproductive aging process in women and to improve our ability to clinically assess and model reproductive aging. Reproductive aging is a continuous process that begins many years prior to menopause. Women in their late 30s and early 40s usually maintain normal menstrual function and ovulatory status, yet fertility in these women is considerably compromised compared to younger women. The primary mechanism of reproductive aging is through the process of ovarian primordial follicle (egg) depletion, a process that exhibits considerable variation between women. As a result, the age at which an individual begins to experience infertility and menstrual cycle changes secondary to follicle depletion also varies significantly and is difficult to predict. The clinical assessment of the number of primordial follicles remaining in the ovary has traditionally relied upon the measurement of ovarian or pituitary hormones such as FSH, estradiol, and inhibin B. Unfortunately, these measures are all indirect and poorly sensitive in the assessment of ovarian reserve. More recently, serum levels of anti-Müllerian hormone (AMH) and the ovarian antral follicle count have been utilized as clinical measures of ovarian reserve. Both have been correlated with chronological age and have some predictive power in determining stimulation quantity (the number of oocytes obtained at the time of egg-recovery) in in-vitro fertilization (IVF) treatment cycles. Reproductive aging in women; however, is more than just the depletion of oocytes from a woman's ovaries, but also involves a decline in oocyte quality. The predictive value of these clinical markers of ovarian reserve with regards to oocyte quality is unknown. Additionally, new tools developed to assess biological aging in other organ systems such as white blood cell telomere length and the measurement of advanced glycation end products (AGEs) through skin autofluoresce
Interventions
- OTHER Women undergoing IVF/ART cycles at OU Physicians Reproductive Health Clinic in Oklahoma City, Oklahoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2009-09 |
| Est. Completion | 2016-12 |
What the finished NCT00988611 record still lists
NCT00988611 is an observational study that tracks outcomes without assigning an intervention. The registered 138 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Women undergoing IVF/ART cycles at OU Physicians Reproductive Health Clinic in Oklahoma City, Oklahoma is the first listed.
NCT00988611 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00988611 about?
NCT00988611 is a clinical study titled "Assisted Reproductive Technology (ART) Predictors Study". The goals of this research proposal are to further our understanding of the reproductive aging process in women and to improve our ability to clinically assess and model reproductive aging. Reproductive aging is a continuous process that begins many years prior to menopause. Women in their late 30s ...
What is the current status of trial NCT00988611?
This trial is currently completed. The enrollment target is 138 participants. The study started on 2009-09. Estimated completion is 2016-12.
What interventions are being tested in trial NCT00988611?
The interventions under investigation include: Women undergoing IVF/ART cycles at OU Physicians Reproductive Health Clinic in Oklahoma City, Oklahoma (OTHER).
Who is sponsoring clinical trial NCT00988611?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
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