Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00987714 · ClinicalTrials.gov registry record · NA
Monitoring Organ Donors to Increase Transplantation Results (MOnIToR)
A NA study of Transplantation, sponsored by University of Pittsburgh.
- Completed
- Registry status
- NA
- Development phase
- 556
- Enrollment target
- 8
- Study locations
NCT00987714 is a NA study of Transplantation that has completed, run by University of Pittsburgh. The registered enrollment target is 556 participants. The trial reports 8 study locations across 7 states.
The verdict
NCT00987714, a NA study of Transplantation, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- NA
- Development phase
- 556 participants
- Enrollment target
- 8
- Study locations
Study Summary
The objective of this study is to determine whether protocol guided resuscitation of brain dead organ donors using Pulse Pressure Variation (PPV) will increase the number of organs transplanted per donor. Specifically the study aims to: 1. improve resuscitation of potential organ donors. 2. improve organ function in donors. 3. increase organ recovery per donor. The investigators will randomize 960 subjects to either protocolized resuscitation (n=480) using a consensus-based PPV-guided algorithm or usual care using a 1:1 randomization scheme. The primary outcome is the mean number of organs transplanted per donor. Secondary outcomes include 6mHFS (six-month hospital-free survival) in the recipients, and mean number of organs procured per donor that are suitable for transplantation (intention to transplant). The study is powered to detect a 0.5 organ increase for transplantation per donor.
Conditions Studied
Interventions
- PROCEDURE Protocolized care
Study Locations (8)
Ohio
- LifeBanc - Cleveland
- Lifeline of Ohio - Columbus
Georgia
- LifeLink of Georgia - Norcross
Oklahoma
- LifeShare of Oklahoma - Oklahoma City
Pennsylvania
- Center for Organ Recovey and Education - Pittsburgh
Tennessee
- Tennessee Donor Services - Knoxville
Texas
- Southwest Transplant Alliance-Dallas - Dallas
Washington
- Lifecenter North West - Bellevue
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 556 participants |
| Start Date | 2009-08 |
| Est. Completion | 2013-03 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00987714
The ClinicalTrials.gov registry entry for NCT00987714 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 556 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Transplantation appearing as the primary indexed condition, and to 1 intervention - of which Protocolized care is the first listed.
NCT00987714 reports 8 study locations spanning 7 distinct geographic areas - top geographies include Ohio, Georgia, Oklahoma.
Frequently Asked Questions
What is clinical trial NCT00987714 about?
NCT00987714 is a clinical study titled "Monitoring Organ Donors to Increase Transplantation Results (MOnIToR)". The objective of this study is to determine whether protocol guided resuscitation of brain dead organ donors using Pulse Pressure Variation (PPV) will increase the number of organs transplanted per donor. Specifically the study aims to: 1. improve resuscitation of potential organ donors. 2. improv...
What is the current status of trial NCT00987714?
This trial is currently completed. It is a NA study. The enrollment target is 556 participants. The study started on 2009-08. Estimated completion is 2013-03.
What conditions does trial NCT00987714 study?
This clinical trial studies the following conditions: Transplantation.
What interventions are being tested in trial NCT00987714?
The interventions under investigation include: Protocolized care (PROCEDURE).
Who is sponsoring clinical trial NCT00987714?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00987714 being conducted?
This trial has 8 study locations across Georgia, Ohio, Oklahoma, Pennsylvania, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Transplantation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.