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NCT00987337 · ClinicalTrials.gov registry record · Phase 2

Filibuvir In Treatment Naive Hepatitis C Virus (HCV) Genotype 1 Subjects

A Phase 2 study, sponsored by Pfizer.

Completed
Registry status
Phase 2
Development phase
288
Enrollment target

NCT00987337: Completed Phase 2 study, sponsored by Pfizer.

NCT00987337 is a Phase 2 study that has completed, run by Pfizer. The registered enrollment target is 288 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (117% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00987337, a Phase 2 study, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 2
Development phase
288 participants
Enrollment target

Study Summary

The primary objective for this study is to determine if the addition of filibuvir to a standard regimen of peginterferon/ribavirin (pegIFN/RBV) significantly increases the proportion of subjects who achieve a sustained viral response (SVR) compared to peginterferon/ribavirin (pegIFN/RBV) therapy alone.

Primary Outcome

For participants who received filibuvir, had undetectable HCV RNA from Week 4 through 24 and discontinued therapy at Week 24, SVR was defined as undetectable plasma HCV RNA levels (\<15 IU/mL) at both Week 24 (End of Treatment \[EOT\]) and Week 72, regardless of the HCV RNA levels between Week 24 and 72. For participants who received filibuvir, had detectable HCV RNA at Week 4 or later and discontinued therapy at Week 48 or who received placebo, SVR was defined as undetectable plasma HCV RNA lev

Interventions

  • DRUG Placebo
  • DRUG Filibuvir

Trial Details

FieldValue
Enrollment Target 288 participants
Start Date 2009-11
Est. Completion 2012-01
Phase Phase 2
Pfizer

1,845 total trials

What the finished NCT00987337 record still lists

NCT00987337 is an interventional study that assigns participants to a tested intervention. The registered 288 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (117% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00987337 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00987337 about?

NCT00987337 is a clinical study titled "Filibuvir In Treatment Naive Hepatitis C Virus (HCV) Genotype 1 Subjects". The primary objective for this study is to determine if the addition of filibuvir to a standard regimen of peginterferon/ribavirin (pegIFN/RBV) significantly increases the proportion of subjects who achieve a sustained viral response (SVR) compared to peginterferon/ribavirin (pegIFN/RBV) therapy alo...

What is the current status of trial NCT00987337?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 288 participants. The study started on 2009-11. Estimated completion is 2012-01.

What interventions are being tested in trial NCT00987337?

The interventions under investigation include: Placebo (DRUG), Filibuvir (DRUG).

Who is sponsoring clinical trial NCT00987337?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00987337's enrollment target sits among peer trials

288 191st of 2000 higher than 1,810 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00987337, the US trial registry maintained by the National Library of Medicine. NCT00987337 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.