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NCT00986999 · ClinicalTrials.gov registry record · Phase 2
Effect of Rosuvastatin on Endothelial Function
A Phase 2 study, sponsored by University of Hawaii.
- Terminated
- Registry status
- Phase 2
- Development phase
- 7
- Enrollment target
NCT00986999 is a Phase 2 study that was terminated before completion, run by University of Hawaii. The registered enrollment target is 7 participants.
The verdict
NCT00986999, a Phase 2 study, was terminated before completion, sponsored by University of Hawaii.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 7 participants
- Enrollment target
Study Summary
Rosuvastatin belongs to a class of medications commonly called "statins" which are medications given for high low density lipoprotein (LDL) 'bad' cholesterol to prevent atherosclerosis (hardening of blood vessels) and lower risk of heart attacks and other circulation problems. Recent studies in the general non-HIV infected population have shown that the beneficial effect of statins in preventing circulation problems is larger than would be expected from lowering of LDL-cholesterol alone. It has been suggested that the additional beneficial effect of statins may be due to the anti-inflammatory effect of statins. The risk of heart attacks and other circulation problems may be high in HIV infected individuals. This may be due to the inflammatory stress effects of HIV. The main purpose of the study is to see if rosuvastatin will have a beneficial effect on the circulatory system in HIV infected individuals even in those who do not have high LDL cholesterol levels. Therefore, in HIV-infected individuals with normal or low LDL cholesterol levels but with evidence of low HDL cholesterol levels which may be a sign of low grade inflammation, the study will look at whether 3 months of rosuvastatin will lead to improvement in brachial artery flow-mediated dilatation (FMD), a marker of early atherosclerosis (hardening of the blood vessels).
Interventions
- DRUG rosuvastatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2009-09 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00986999
The ClinicalTrials.gov registry entry for NCT00986999 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Hawaii, which has 77 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which rosuvastatin is the first listed.
NCT00986999 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00986999 about?
NCT00986999 is a clinical study titled "Effect of Rosuvastatin on Endothelial Function". Rosuvastatin belongs to a class of medications commonly called "statins" which are medications given for high low density lipoprotein (LDL) 'bad' cholesterol to prevent atherosclerosis (hardening of blood vessels) and lower risk of heart attacks and other circulation problems. Recent studies in the ...
What is the current status of trial NCT00986999?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 7 participants. The study started on 2009-09.
What interventions are being tested in trial NCT00986999?
The interventions under investigation include: rosuvastatin (DRUG).
Who is sponsoring clinical trial NCT00986999?
This trial is sponsored by University of Hawaii, which has 77 total clinical trials registered on ClinicalTrials.gov.
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