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NCT00986310 · ClinicalTrials.gov registry record · NA

Efficacy of Fluoxetine in Reducing Ictal Hypoventilation in Patients With Partial Epilepsy

A NA study of Uncontrolled Partial Epilepsy and Ictal Hypoventilation, sponsored by University of California, Davis.

Completed
Registry status
NA
Development phase
2
Enrollment target
1
Study location

NCT00986310 is a NA study of Uncontrolled Partial Epilepsy and Ictal Hypoventilation that has completed, run by University of California, Davis. The registered enrollment target is 2 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT00986310, a NA study of Uncontrolled Partial Epilepsy and Ictal Hypoventilation, has completed, sponsored by University of California, Davis.

COMPLETED
Registry status
NA
Development phase
2 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine the effects of fluoxetine on breathing mechanisms during seizures. Patients with partial epilepsy commonly have changes in their breathing mechanisms during seizures. These changes may increase the risk of serious side effects from seizures, including sudden unexplained death in epilepsy (SUDEP), which affects 2-10 per 1000 patients with epilepsy each year. Fluoxetine (Prozac) may help to stimulate breathing through its actions in the brain and has been shown to improve breathing changes seen with seizures in certain animals. Fluoxetine is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain, at synapses, the junctions at which nerve cells in the brain communicate. Fluoxetine is currently approved by the United States Food and Drug Administration (FDA) for the treatment of patients with Major Depressive Disorder, Obsessive Compulsive Disorder, Bulimia Nervosa, Panic Disorder and Premenstrual Dysphoric Disorder.

Interventions

  • DRUG Placebo
  • DRUG Fluoxetine

Study Locations (1)

California

  • University of California, Davis - Sacramento

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2009-08
Est. Completion 2012-06
Phase NA

Sponsor

University of California, Davis

657 total trials

What the Registry Record Tells You About NCT00986310

The ClinicalTrials.gov registry entry for NCT00986310 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Uncontrolled Partial Epilepsy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00986310 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00986310 about?

NCT00986310 is a clinical study titled "Efficacy of Fluoxetine in Reducing Ictal Hypoventilation in Patients With Partial Epilepsy". The purpose of this study is to determine the effects of fluoxetine on breathing mechanisms during seizures. Patients with partial epilepsy commonly have changes in their breathing mechanisms during seizures. These changes may increase the risk of serious side effects from seizures, including sudden...

What is the current status of trial NCT00986310?

This trial is currently completed. It is a NA study. The enrollment target is 2 participants. The study started on 2009-08. Estimated completion is 2012-06.

What conditions does trial NCT00986310 study?

This clinical trial studies the following conditions: Uncontrolled Partial Epilepsy, Ictal Hypoventilation.

What interventions are being tested in trial NCT00986310?

The interventions under investigation include: Placebo (DRUG), Fluoxetine (DRUG).

Who is sponsoring clinical trial NCT00986310?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00986310 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.