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NCT00985192 · ClinicalTrials.gov registry record · Phase 2

Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer

A Phase 2 study, sponsored by Translational Oncology Research International.

Completed
Registry status
Phase 2
Development phase
49
Enrollment target

NCT00985192: Completed Phase 2 study, sponsored by Translational Oncology Research International.

NCT00985192 is a Phase 2 study that has completed, run by Translational Oncology Research International. The registered enrollment target is 49 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00985192, a Phase 2 study, has completed, sponsored by Translational Oncology Research International.

COMPLETED
Registry status
Phase 2
Development phase
49 participants
Enrollment target

Study Summary

RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well everolimus works in treating patients with previously treated unresectable or metastatic esophageal cancer or stomach cancer.

Primary Outcome

Disease control rate (DCR), defined as complete response (CR) + partial response (PR) + stable disease (SD) according to Response Evaluation Criteria In Solid Tumors (RECIST) criteria.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG everolimus

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2009-09
Est. Completion 2014-05
Phase Phase 2

What the finished NCT00985192 record still lists

NCT00985192 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% lower).

The record links to 0 conditions, and to 2 interventions - of which laboratory biomarker analysis is the first listed.

NCT00985192 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00985192 about?

NCT00985192 is a clinical study titled "Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer". RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well everolimus works in treating patients with previously treated unresectable or metastatic esophag...

What is the current status of trial NCT00985192?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 49 participants. The study started on 2009-09. Estimated completion is 2014-05.

What interventions are being tested in trial NCT00985192?

The interventions under investigation include: laboratory biomarker analysis (OTHER), everolimus (DRUG).

Who is sponsoring clinical trial NCT00985192?

This trial is sponsored by Translational Oncology Research International, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00985192's enrollment target sits among peer trials

49 1261st of 2000 higher than 736 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00985192, the US trial registry maintained by the National Library of Medicine. NCT00985192 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.