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NCT00984594 · ClinicalTrials.gov registry record · Phase 3
Evaluation of a Composite Cancellous and Demineralized Bone Plug (CR-Plug) for Repair of Knee Osteochondral Defects
A Phase 3 study, sponsored by RTI Surgical.
- Terminated
- Registry status
- Phase 3
- Development phase
- 4
- Enrollment target
NCT00984594: Clinical Trial Phase 3 study, sponsored by RTI Surgical.
NCT00984594 is a Phase 3 study that was terminated before completion, run by RTI Surgical. The registered enrollment target is 4 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00984594, a Phase 3 study, was terminated before completion, sponsored by RTI Surgical.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 4 participants
- Enrollment target
Study Summary
The objective of this study is to determine how effective a plug made out of human bone (called "CR-Plug") will be in the treatment of smaller, focal defects (like the injury the patient has to their knee).
Primary Outcome
The outcome at 24 months as measured by the Knee injury and Osteoarthritis Outcome Score (KOOS). Scores are transformed to a 0-100 scale, with zero representing extreme knee problems and 100 representing no knee problems as common in orthopaedic scales and generic measures. Scores between 0 and 100 represent the percentage of total possible score achieved.
Interventions
- OTHER Primary injury site
- OTHER Backfill site
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2009-01 |
| Est. Completion | 2012-02 |
| Phase | Phase 3 |
Why NCT00984594 stopped before completion
NCT00984594 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Primary injury site is the first listed.
NCT00984594 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00984594 about?
NCT00984594 is a clinical study titled "Evaluation of a Composite Cancellous and Demineralized Bone Plug (CR-Plug) for Repair of Knee Osteochondral Defects". The objective of this study is to determine how effective a plug made out of human bone (called "CR-Plug") will be in the treatment of smaller, focal defects (like the injury the patient has to their knee).
What is the current status of trial NCT00984594?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 4 participants. The study started on 2009-01. Estimated completion is 2012-02.
What interventions are being tested in trial NCT00984594?
The interventions under investigation include: Primary injury site (OTHER), Backfill site (OTHER).
Who is sponsoring clinical trial NCT00984594?
This trial is sponsored by RTI Surgical, which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00984594's enrollment target sits among peer trials
4 1998th of 2000 higher than 2 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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