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NCT00980694 · ClinicalTrials.gov registry record · Phase 1

Bioavailability of Ubiquinol in Huntington Disease

A Phase 1 study, sponsored by University of Rochester.

Completed
Registry status
Phase 1
Development phase
6
Enrollment target

NCT00980694: Completed Phase 1 study, sponsored by University of Rochester.

NCT00980694 is a Phase 1 study that has completed, run by University of Rochester. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00980694, a Phase 1 study, has completed, sponsored by University of Rochester.

COMPLETED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

The death of brain cells in Huntington Disease (HD) is thought to be associated with a lack of normal cell energy and harmful brain substances called free radicals. Coenzyme Q10 (CoQ) is a marketed nutritional supplement that may prove useful in HD because it increases cell energy and combats free radicals. Most studies of CoQ have looked at only one formulation of CoQ ("ubiquinone") in HD. The purpose of the study is to find out if people that switch from the common formulation of CoQ ("ubiquinone") to a different formulation ("ubiquinol") have higher levels of CoQ in their blood after taking the same dose. The investigators also want to find out if this different formulation is tolerable for individuals with HD.

Interventions

  • DIETARY_SUPPLEMENT ubiquinol

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2009-09
Est. Completion 2012-07
Phase Phase 1
University of Rochester

636 total trials

What the finished NCT00980694 record still lists

NCT00980694 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which ubiquinol is the first listed.

NCT00980694 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00980694 about?

NCT00980694 is a clinical study titled "Bioavailability of Ubiquinol in Huntington Disease". The death of brain cells in Huntington Disease (HD) is thought to be associated with a lack of normal cell energy and harmful brain substances called free radicals. Coenzyme Q10 (CoQ) is a marketed nutritional supplement that may prove useful in HD because it increases cell energy and combats free r...

What is the current status of trial NCT00980694?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2009-09. Estimated completion is 2012-07.

What interventions are being tested in trial NCT00980694?

The interventions under investigation include: ubiquinol (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT00980694?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00980694's enrollment target sits among peer trials

6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00980694, the US trial registry maintained by the National Library of Medicine. NCT00980694 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.