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COMPLETED Phase 2

Oral Triple Combination Antiviral Drug Therapy for Treatment of Influenza A in Immunocompromised Subjects

NCT00979251 · View on ClinicalTrials.gov ↗

Study Summary

This Phase 2, open label, randomized study will investigate the virologic benefit, clinical efficacy, safety, and tolerability of amantadine and ribavirin with oseltamivir (TCAD) versus oseltamivir monotherapy for the treatment of all strains of influenza A in immunocompromised adult and pediatric subjects.

Conditions Studied

Interventions

  • DRUG Oseltamivir Phosphate
  • DRUG ADS-8902

Study Locations (20)

California

  • Adamas Investigational Site — San Francisco
  • Adamas Investigational Site — San Francisco
  • Adamas Investigational Site — San Francisco

Florida

  • Adamas Investigational Site — Hollywood
  • Adamas Investigational Site — Miramar
  • Adamas Investigational Site — Pinellas Park

New South Wales

  • Adamas Investigational Site — Darlinghurst
  • Adamas Investigational Site — Herston
  • Adamas Investigational Site — Sydney

Washington

  • Adamas Investigational Site — Seattle
  • Adamas Investigational Site — Tacoma

Hawaii

  • Adamas Investigational Site — Honolulu

Kentucky

  • Adamas Investigational Site — Owensboro

Louisiana

  • Adamas Investigational Site — New Orleans

Nevada

  • Adamas Investigational Site — Las Vegas

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2009-09
Est. Completion 2011-08
Phase Phase 2

Sponsor

Adamas Pharmaceuticals

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00979251

The ClinicalTrials.gov registry entry for NCT00979251 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Adamas Pharmaceuticals, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Influenza appearing as the primary indexed condition, and to 2 interventions — of which Oseltamivir Phosphate is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00979251 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Florida, New South Wales. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00979251 about?

NCT00979251 is a clinical study titled "Oral Triple Combination Antiviral Drug Therapy for Treatment of Influenza A in Immunocompromised Subjects". This Phase 2, open label, randomized study will investigate the virologic benefit, clinical efficacy, safety, and tolerability of amantadine and ribavirin with oseltamivir (TCAD) versus oseltamivir monotherapy for the treatment of all strains of influenza A in immunocompromised adult and pediatric s...

What is the current status of trial NCT00979251?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2009-09. Estimated completion is 2011-08.

What conditions does trial NCT00979251 study?

This clinical trial studies the following conditions: Influenza. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00979251?

The interventions under investigation include: Oseltamivir Phosphate (DRUG), ADS-8902 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00979251?

This trial is sponsored by Adamas Pharmaceuticals, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00979251 being conducted?

This trial has 20 study locations across California, Florida, Hawaii, Kentucky, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial